The Pharmacy Times® C. Difficile Resource Center is a comprehensive resource for clinical news and expert insights on issues related to Clostridium difficile, a bacteria that causes colitis, a serious inflammation of the colon.
April 1st 2024
Scientists hypothesize that fecal microbiota transplant restores the recipient’s gut microbiota to an environment that mimics the healthy donor’s microbiota
Microbiome Therapeutic Demonstrates Reduction of C. Difficile Recurrence
November 8th 2021SER-109, an investigational, oral, biologically-sourced microbiome therapeutic designed to reduce recurrence of C. difficile infection (CDI), demonstrated a 31.1% absolute reduction in the rate of CDI recurrence over 12 weeks compared to placebo
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New Research Confirms High Toxin Levels Linked to More Severe C. Difficile Infection
November 1st 2021The concentration of C. diff toxins in the stool was linked to how sick patients were at the time of diagnosis and was associated with adverse outcomes, including the risk of infection returning after treatment.
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Clinical Development Program Shows Promise for Microbiome-Based Therapeutics in Recurrent C. Diff
October 14th 2021Lindy Bancke, PharmD, head of clinical development at Rebiotix Inc, said the clinical development program of RBX2660 is showing promise in the treatment of recurrent C. Difficile infection.
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Patent Filed for Application of Ibezapolstat in the Treatment of C. Difficile Infection
July 12th 2021This action follows a recently completed phase 2a clinical trial, which demonstrated that 100% of the 10 enrolled patients met the study's primary and secondary efficacy endpoints of clinical cure at end of treatment as well as sustained clinical cure with no recurrence of CDI when examined on a 28-day follow-up visit.
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Stewardship Program Helps Hospitals Reduce Antibiotic Use, Prevent Bacterial Infections
April 5th 2021The overuse of antibiotics in hospitals can lead to the emergence of drug-resistant strains of bacteria or outbreaks of infections by bacteria, such as Clostridiodes difficile (C. difficile).
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