Oncology

Olaparib (Lynparza) double objective response rate compared with other breast cancer drugs.

Malignant peripheral nerve sheath tumors are currently incurable.

Top news of the day from across the health care landscape.

First Abbreviated New Drug Application filed for sofosbuvir (Sovaldi).

FDA approves shorter administration periods and new dosing options for nivolumab (Opdivo).

Research into gene variants may improve targeted treatments for pancreatic cancer.

Officials with the FDA have approved ibalizumab-uiyk (Trogarzo, TaiMed Biologics), the first antiretroviral medication for adults with HIV who cannot be successfully treated with other therapies.

A new direct-to-consumer test analyzes saliva for 3 BRCA variants that may elevate the risk of various types of cancer.

A new direct-to-consumer test analyzes saliva for 3 BRCA variants that may elevate the risk of various types of cancer.

Top news of the week from Specialty Pharmacy Times.

ERK inhibitors may increase the efficacy of other anti-cancer drugs.

Research highlights the need for new prostate specific antigen testing guidelines.

The National Comprehensive Cancer Network seeks to address issues related to treating HIV-positive patients with cancer, such as the potential for drug interactions.

The FDA previously approved abemaciclib for use in combination with fulvestrant in women with HR+/HER2- advanced breast cancer with disease progression following endocrine therapy.

Top news of the week from Specialty Pharmacy Times.

The FDA recently approved durvalumab (Imfinzi) for the treatment of patients with stage 3 non-small cell lung cancer (NSCLC) whose tumors are unresectable and whose disease has not progressed following treatment with chemoradiation.

Enzalutamide (Xtandi) demonstrates a significant reduction in metastasis or death from castration-resistant prostate cancer

Lorlatinib was designed to bypass non-small cell lung cancer mutations that promote drug resistance

Apalutamide (Erleada) was approved based on metastasis-free survival, which is a new clinical endpoint.

Smoking and alcohol consumption may exacerbate the risk of esophageal cancer associated with hot tea.

FDA expands the indication of abiraterone acetate (Zytiga) to include more patients with prostate cancer.

The risk of non-Hodgkin's lymphoma is elevated in patients with hepatitis C virus.

Immunotherapy combination beneficial for patients with lung cancer with a high tumor mutation burden.

Chronic HCV infection has been linked to low serum zinc and low metallothioneins expression in liver cells.

Ion channel inhibitors show promise reducing the high cost of conventional hepatitis C virus antiviral therapies.

The combination of nivolumab (Opdivo) and ipilimumab (Yervoy) improved progression-free survival (PFS) compared with chemotherapy in treatment-naïve patients with high tumor mutation burden (TMB) non–small cell lung cancer (NSCLC).

Newly-discovered gene mutations could double the risk of breast cancer.

A single blood test could diagnose 8 different types of cancer simultaneously.

Real-world evidence is becoming increasingly important for the development of treatment strategies in oncology.