Hospital

The investigators analyzed a panel of antibodies generated in response to the Pfizer COVID-19 vaccine and found that delta was unable to evade all but 1 of the antibodies tested.

In clinical trials, empagliflozin significantly reduced the relative risk of the primary composite endpoint of time to cardiovascular death or hospitalization for heart failure by 25%.

Specialty pharmacists’ roles have grown in new and exciting ways in recent years, and those changes have directly impacted health outcomes for all specialty patients, including patients with HIV.

Widespread COVID-19 booster shot administration is pending FDA approval and recommendation by the Advisory Committee on Immunization Practices.

The continued approval for this indication may be subject upon verification and description of clinical benefit in a confirmatory trial.

Approved by the FDA on June 29, 2020, the pertuzumab, trastuzumab, and hyaluronidase-zzxf combination therapy with chemotherapy offers several advantages to the standard treatment of pertuzumab plus trastuzumab with chemotherapy for breast cancers with HER2 overexpression.

These findings could lead to improved therapies and prolonged survival for patients with metastatic TNBC, according to the study authors.

English discussed the challenges and highlights of her time in the trial, in addition to what she feels health care professionals should learn from her own treatment experience.

Dennis Wright, senior director of product marketing for Central Pharmacy Compounding and Dispensing at Omnicell, discusses methods of addressing the rising rate of hospital pharmacist burnout through automation and technology-enabled services.

What many preceptors may not realize is that in addition to learning about practice settings, all graduates of pharmacy schools in the United States must also be able to demonstrate leadership, innovation, and entrepreneurship.

Amesh Adalja, MD, FIDSA, FACP, FACEP, said that the efficacy of COVID-19 booster vaccines against variants of concern is still relatively unknown, although administering the third shots does increase antibodies as expected.

Non-alcoholic steatohepatitis is the most severe form of non-alcoholic fatty liver disease.

Atrial fibrillation, bleeding, infection, and other adverse events may occur with this therapy.

This has caused an ongoing problem with mistrust in many vaccines and medications, since there is still uncertainty surrounding how they affect other races and ethnicities.

Specific infection-fighting cells of the immune system found to be downregulated, offering a potential clue to the cause of prolonged COVID-19 illness in children.

The FDA has granted orphan drug designation to CFT7455 for the treatment of multiple myeloma, according to a press release from manufacturer C4 Therapeutics.

The designation highlights the need for new treatment options for patients with platinum-resistant ovarian cancer and the significant treatment potential of IN10018, according to a press release from InxMed, the manufacturer of the novel drug.

An announcement from CDC officials recommending COVID-19 boosters for all adults could come as soon as this week, although doses would only be widely administered once the FDA formally approved the vaccines.

Ridinilazole is not currently approved for use by any regulatory authority.

Physicians may ask for either or both of comprehensive metabolic panel or complete blood count tests every 3 to 6 months, based on the conditions patients have.

The approval marks the first HIF-2α inhibitor therapy approved in the United States for some types of Von Hippel-Lindau disease-associated tumors.

Approval sought for oportuzumab monatox-qqrs (Vicinium) for the treatment of BCG-unresponsive non-muscle invasive bladder cancer (NMIBC), which was previously granted priority review by the FDA.

The pandemic taught the pharmacy to provide a deeper level of personalized care and communication than in the past.

Julie Bullock, VP, global head of clinical pharmacology and translational medicine at Certara, discusses the FDA’s new guidance Project Optimus, which addresses issues relating to dose optimization in clinical trials assessing oncology drugs.

Daratumumab and hyaluronidase-fihj (Darzalex Faspro, Janssen) was approved in July in combination with pomalidomide and dexamethasone for the treatment of patients with multiple myeloma following their first or subsequent relapse.

New treatments show promise for patients with KRAS G12C–mutated disease.

The FDA recently authorized COVID-19 vaccine booster shots for immunocompromised individuals, who comprise about 3% of the US population.

Analyzing how off-target antibodies may be undermining HIV vaccine prototypes allows for design improvements.

The FDA approved pembrolizumab plus lenvatinib for the first-line treatment of adult patients with advanced RCC.

Patients with microsatellite stable (MSS) colorectal cancer, which represents 95% of all metastatic colorectal cancer cases, are more responsive to checkpoint blockade immunotherapy if the patient’s tumors have not spread to the liver.