Jill Murphy, Associate Editor

A presentation at the Society of Hematologic Oncology 2021 Annual Meeting reviewed the treatment of amyloidosis in multiple myeloma.

Dr. Jason Liu and his colleagues hoped to assess the use of maintenance durvalumab based on patient and physician characteristics among individuals with stage 3 NSCLC in the United States.

Presenter Maria-Victoria Mateos, MD, PhD, University Hospital of Salamanca-IBSAL, Salamanca, Spain, discussed how optimal sequencing in MM has changed from those outlined in the older EU guidelines.

New research has found that the relative cardiovascular safety of different types of androgen deprivation therapy (ADT) for prostate cancer remains unresolved after the PRONOUNCE trial was terminated early.

The research team analyzed the associations between maternal diabetes before or during pregnancy and the risk of high refractive error (RE), which are conditions in which there is a failure of the eye to properly focus images on the retina.

Because asparaginase is used exclusively in ALL, most adult oncologists do not administer it routinely.

This drug class works by interfering with the ability of cancer cells to repair themselves after experiencing damage to their DNA, but how PARP inhibitors selectively kill cancer cells was previously unknown.

RSV is defined as a seasonal illness that starts in the fall months and peaks during the winter when other respiratory illnesses are more common.

Treatment-emergent serious adverse events were reported more frequently in patients with PVD, which was likely due to their more advanced disease, according to the researchers.

During the trial, the research team wanted to look at aggressive B cell lymphomas and the outcomes comparing white patients versus minorities.

Study indicates that patients with asthma should continue taking their asthma medications during the COVID-19 pandemic.

Compared to women who followed the Portfolio Diet less frequently, those with the closest alignment were 11% less likely to develop any type of cardiovascular disease, 14% less likely to develop coronary heart disease, and 17% less likely to develop heart failure.

AZD7442 reduced the risk of developing symptomatic COVID-19 by 77% compared to placebo.

Further, their status was evaluated at 14, 21, and 28 days after treatment, and at each point, the numbers of hospitalization were significantly lower in the treated group.

The AHA worked with a team of leading health authorities to develop the advisory, which highlights recommendations, algorithms, and guidance for health care professionals and researchers who specialize in heart and brain health.

Doses of the influenza live, intranasal (Flumist Quadrivalent, AstraZeneca) vaccine are now available in the United States in time for the 2021-2022 influenza season.

The data represent teens most likely to benefit from the vaccination and are meant to offer reassurance to parents and clinicians, even with small study numbers.

They added that side chains are linked to nitrogens in the molecular backbone, forming a structure that resists enzymes.

New research provides a further explanation for how an infection by influenza A virus followed by S. pneumoniae superinfection causes severe pneumonia and a high death rate.

This designation could shorten the FDA review period to 8 months compared to the 12 months under Standard Review.

For the study, approximately 20,000 people were followed over a span of 4 years, which showed that reports of marijuana use peaked at 9% for patients with cancer versus 14% among those with no cancer history.

The study, conducted by Augusta University, was among the first to examine factors related to vaccine hesitancy among a large African American community sample, according to the authors.

This research lays the foundation for future clinical trials aimed at investigating whether moderate to vigorous exercise can minimize “chemo brain,” which is a decline in cognitive function many patients with breast cancer experience.

Additionally, among this population, combining aerobic exercise with a moderate reduction in daily calories resulted in greater improvements in aortic stiffness versus exercise only or exercise plus a more restrictive diet.

According to Fenn, these numbers are significant when considering the types of errors that are likely to occur in sleep-deprived operators, such as surgeons or police officers, and the 4% decrease in errors could potentially save lives.

The continued approval for this indication may be subject upon verification and description of clinical benefit in a confirmatory trial.

This has caused an ongoing problem with mistrust in many vaccines and medications, since there is still uncertainty surrounding how they affect other races and ethnicities.

The FDA has granted orphan drug designation to CFT7455 for the treatment of multiple myeloma, according to a press release from manufacturer C4 Therapeutics.