Jill Murphy, Associate Editor

Study finds early career workers were more likely to disengage during the pandemic, such as by showing a lack of interest or becoming cynical about work.

IPX203 is a novel, oral formulation of carbidopa/levodopa extended-release capsules.

Agency’s action date is May 21, 2023, for the first subcutaneous bispecific antibody approved for the treatment of large B-cell lymphoma.

Although long-term health issues from COVID-19 are a major public health concern, evidence on post-acute COVID-19 syndrome, or post-COVID-19, is still limited, specifically among children and adolescents.

The objective of the study was to estimate recent trends in cigarette use and health insurance coverage for US adults with and without mental health and SUD.

Demand for treatment of anxiety and depression remained high for the third consecutive year as the demand for the treatment of trauma- and stressor-related and substance use disorders has increased.

Individuals with COVID-19 reinfections were twice as likely to die and three times more likely to be hospitalized than those who did not have COVID-19 multiple times.

New system combines computational and experimental techniques to map evolutionary cancer lineages in their natural habitat of human tissue.

Bepirovirsen produced sustained clearance of hepatitis B virus and hepatitis B surface antigens.

Dapagliflozin is the first SGLT2 inhibitor approved by the FDA for treatment of patients with heart failure (NYHA class II-IV) with reduced ejection fraction.

Patients administered 75 mg or higher of olpasiran every 12 weeks had a 95% or greater reduction in Lp(a) compared to placebo at week 36.

Five hours or less hours of sleep per night at 50 years of age was associated with a 25% higher risk of mortality over 25 years of follow-up.

Patients with Alzheimer disease administered gantenerumab did experience slower clinical decline, however, it was not deemed statistically significant.

Guselkumab (Tremfya) is a fully human selective IL-23 inhibitor therapy FDA-approved for the treatment of adults with active psoriatic arthritis and with moderate to severe plaque psoriasis.

In a 2019 survey, middle-aged participants were considerably more apprehensive about getting vaccinated than younger groups, which was not the case in the 2022 survey.

Anxiety disorders include generalized anxiety, social anxiety, panic disorder, and fear of certain places or situations, including crowds and public transportation.

Approximately 80% of all HIV infections among teens are from the gay and bisexual population.

Evolocumab found to reduce reduced adverse cardiovascular events in combination with statin therapy compared to placebo plus statin therapy.

NVX-CoV2373 is a protein-based vaccine developed from the genetic sequence of the first strain of SARS-CoV-2.

Dapagliflozin and standard of care found to slow the decline in kidney function and lower the incidence of kidney failure.

Despite evidence of a higher risk of myocarditis or pericarditis with COVID-19 vaccination, immunization should still be recommended because the benefits likely outweigh the harms, study shows.

Direct-acting antivirals have high efficacy for hepatitis C, however, patients with advanced liver scarring are at risk for the development of secondary diseases.

Study shows there are 2.5 times more breast cancer survivors since the last estimate was conducted in 2007.

FDA committee voted that trial data do not support the benefits outweighing the risks in patients aged 12 to 17 years and children aged 4 to 11 years for the use of albuterol/budesonide in the treatment of asthma.

Research indicates that administering vitamin C to dendritic cells produces more consistent activation of genes involved in the immune response.

The American Heart Association issued a dietary guidance in 2021 suggesting that adults consume a variety of fruits and vegetables, choose whole grains instead of refined grains, eat healthy protein sources and lean cuts of meat, and substitute nonfat and low-fat dairy products for full-fat versions, among other measures.

In 2020, heart disease death rates increased in adults across all age, sex, racial and ethnic groups, specifically among younger adults and non-Hispanic Black adults.

Retinal vein occlusion is the second most common cause of vision loss from retinal vascular diseases.

A 30-µg booster dose of the Omicron BA.4/BA.5-adapted bivalent vaccine may produce a higher level of protection against the Omicron BA.4 and BA.5 sublineages than the original COVID-19 vaccine.

Although the number of new HIV infections in the world have declined, there are still regions that are geographically heterogenous that have reported an increase in infection rates.