Jill Murphy, Associate Editor

Despite the approval of exciting new therapies for heart failure, there are still some challenges that need to be addressed to improve patient outcomes.

Empagliflozin (Jardiance, Boehringer Ingelheim/Lilly) tablets are the first and only heart failure therapy to demonstrate a statistically significant risk reduction in cardiovascular death.

Health care professionals need to meet their patients at their health level and find a diet and medication regimen that works for them to best reduce the risk of cardiovascular events.

Investigators followed men and women aged 20 to 40 years without pre-existing disease, and findings indicate that obesity and physical inactivity increase the impact of the disease.

Analysis is based on 2018 hospitalization rates of patients with cardiovascular disease in New Jersey.

Measurements may not be accurate in those with darker tones, according to analysis to be presented at the American College of Cardiology’s 71st Annual Scientific Session.

Despite their lower antibody responses, patients who are vaccinated receive protection from SARS-CoV-2 infection and severe disease.

Mindfulness-based cognitive therapy helps change feelings and thoughts about experiences, minimizing depressive episodes, analysis indicates.

Analysis to be presented at the American College of Cardiology’s 71st Annual Scientific Session is based on the health records of 495,386 patients.

Previous research has shown that genetic factors contribute immensely to the risk of migraine.

Factors such as economic stability and education access can be categorized into social determinants of health.

Session at the American Pharmacists Association Annual Meeting discusses the importance of naloxone in reducing the burden of the opioid epidemic.

The research team used the National Cancer Institute’s Surveillance, Epidemiology, and End Results database, which provides nationwide information on cancer statistics.

Finch was still able to continue dosing patients in its past-ongoing PRISM-EXT phase 2 open-label trial of CP101 in recurrent CDI, because the CP101 lots used for PRISM-EXT were manufactured from material donated prior to December 1, 2019.

In the third part of the series, we further explore the factors that contribute to overall happiness in a position.

The commission “Time for United Action on Depression,” authored by 25 experts from 11 countries, seeks to unify global efforts among governments, health care providers, researchers, people living with depression, and their families to improve care and prevention, fill knowledge gaps, and increase awareness.

The risk of death from CVD was approximately 15% lower for those with the highest vegetable intake compared to the lowest vegetable intake.

Enhanced tools in the field of structural biology may reveal new insights into HIV that could lead to a vaccine to protect against the virus progessing to AIDS.

This will increase Moderna’s vaccine catalog to 5, including vaccines against cytomegalovirus (CMV), Epstein-Barr virus (EBV), and HIV, in addition to the immunizations for HSV, and VZV.

Novel C. difficile infection (CDI) vaccine shows promise lowering the severity of CDI and in preventing medically attended CDI.

COVID-19 vaccines are effective in preventing severe infection resulting in hospitalization, but protection wanes after 6 months.

New strategies are needed to increase HIV prevention and testing efforts among high-risk communities.

Although biologic changes may occur in the body that affect the brain, nonbiologic changes, such as social isolation, can also be a part of it but the reasons are not completely clear, according to the study.

The researchers aimed to identify the factors that may influence the risk of statin intolerance.

The study met its primary goal by demonstrating pharmacokinetic equivalence in patients who switched multiple times between treatment with the 2 medicines.

During 90 minutes of exercise, the participants focused on maintaining a pace that kept their heart race approximately 120-140 beats per minute rather than focusing on the distance.

The results of a new study indicate that early initiation of treatment with combined antiretroviral therapy (cART) leads to better outcomes in patients coinfected with HIV and tuberculosis (TB).

In a phase 3 study, there were clinically and statistically significant changes observed from baseline to week 6 in the Montgomery-Åsberg Depression Rating Scale (MADRS) total score for patients treated with cariprazine at 1.5 mg/day versus the placebo.

Investigators used SC144, an FDA-approved molecule, to find a new pathway for a generation of nonhormonal contraceptives.

During the period in which Omicron was the dominant variant, the researchers found that fewer patients died while hospitalized compared with those admitted when the Delta variant was dominant.