Jill Murphy, Associate Editor

Although prevention decreased with time, a third booster dose was still highly effective at preventing severe illness with COVID-19.

Cohort H of the phase 1b/2 EV-103 trial enrolled patients with MIBC who were eligible for surgical treatment but ineligible for cisplatin-based chemotherapy.

Through the 240 weeks, numerically small median changes in eGFR and stable TC:HDL ratios were observed in both studies.

The drug pipeline is insufficient to meet the threat of antimicrobial resistance, and policy reforms are critically needed, according to the Biotechnology Innovation Organization.

All the participants were in the Beating Lung Cancer in Ohio study, which started before the COVID-19 pandemic.

Prior studies indicate that CPAP treatment can significantly decrease sleepiness and depression while also protecting against high blood pressure.

The use of a unique trimer to produce tier-2 neutralizing antibodies may help fight HIV.

Following the first 3 days after a COVID-19 diagnosis, the risk of stroke quickly decreased.

The vaccine targets the outer surface protein A of Borrelia burgdorferi, which is the bacteria that cause Lyme disease.

Although the researchers were able to find an association between a heart attack and faster cognitive decline, the findings did not establish that a heart attack directly causes cognitive decline.

During that time period, patients with high-deductible health plans spent on average $133 per 30-day supply, a cost threshold associated with a more than 50% rate of prescription abandonment, according to the researchers.

The paper also outlines the cardiovascular effects during sports of doping substances, prescribed and OTC medicines, legal performance-enhancing supplements, and experimental drugs.

The research team looked at tumor samples, CT scans, and immune markers from the patients, finding that those who had taken part in the exercise program showed a better response to the chemotherapy.

Although COVID-19 vaccination rates have increased since the survey was initially conducted, the researchers noted that their results are important when considering the possibility of an annual COVID-19 vaccine.

The research team suggests that healthy weight maintenance throughout adulthood is crucial in preventing colorectal adenoma.

The trial studied 3 dosing regimens of asparaginase erwinia chrysanthemi (recombinant)-rywn, with cohort 1a receiving 25 mg/m2administered Monday and Wednesday and 50 mg/m2administered on Friday.

The research team found that levels of depression are at least 3 times higher than before the COVID-19 pandemic.

Further, the 1-year update suggests that Cohort 6 toxicity management strategy can improve certain AEs without compromising the activity of axicabtagene ciloleucel.

The men were assessed for neuroticism—or the tendency to interpret situations as stressful, threatening, or overwhelming—and worry levels through 2 mail-in surveys.

The participants were asked to provide information on their age, ethnicity, region of residence, income, education, lifestyle, weight, medical history, diet, and supplement use.

Wright said that there would be 1 drug that could inhibit the reactivation of all 9 of the herpesviruses.

Previous studies provided proof of concept that peanut oral immunotherapy could be given safely to young children and have a therapeutic effect.

The study will have 3 cohorts examining different regimens of the current Pfizer-BioNTech COVID-19 vaccine or an omicron-based vaccine and will use participants from the phase 3 COVID-19 booster study.

The analysis of 204 countries and territories reveals that AMR is now a leading cause of death worldwide, which is higher than HIV/AIDS or malaria.

The tislelizumab combination met the primary endpoint of OS in patients with programmed death ligand 1 (PD-L1) expression, with additional follow-up needed to assess OS benefits in the intention-to-treat population.

Some study limitations include that follow-up data were missing for some patients who dropped out of the study during the follow-up stages and the timing of the follow-up echocardiograms were random and driven by preference versus standard protocol.

These findings suggest people with indications for PrEP may confront an access barrier if they live in a state that restricts scope of practice, according to the study.

The kit helps detect SARS-CoV-2 RNA in nasopharyngeal, anterior nasal, mid-turbinate nasal or oropharyngeal swab specimens from individuals suspected of COVID-19 by their health care provider.

The research team conducted a systematic review to collect the available published evidence on the topic and then combined the results using a process called meta-analysis.