Jennifer Nessel, Assistant Editor

An analysis of efficacy and safety outcomes in patients receiving perampanel as first adjunctive antiepileptic drug found that almost half of the patients were seizure-free.

The EGFR/RAS/MEK pathway may serve as a predictive biomarker for palbociclib plus fulvestrant resistance and offer therapeutic targets to overcome resistance in patients with ER-positive/HER2-negative breast cancer.

Researchers used an epidermal growth factor (EGF)-conjugated anthrax toxin that, after targeting EGFR, was internalized and triggered apoptosis in exposed bladder cancer cells.

Approximately 2 out of 6 study participants tested positive after vaping cannabis that contained 0.39% THC using urine testing methods.

The CDC reported progress with the current status of the 3 strategies within the national initiative, Ending the HIV Epidemic: A Plan for America.

A retrospective cohort study was the second largest evaluation to date of sodium polystyrene sulphonate use and safety in patients with chronic kidney disease.

Icosapent ethyl is the first FDA-approved prescription form of fish oil to reduce cardiovascular risk among patients with triglyceride levels as an add-on to maximally tolerated statin therapy.

In this study, researchers wanted to evaluate the frequency of reduced immunoglobulin concentrations and its association with immunotherapy and disease course in 2 independent cohorts with multiple sclerosis.

A report suggests that addressing financial barriers to antiretroviral therapy adherence may improve levels of viral suppression.

The etonogestrel/ethinyl estradiol vaginal ring is a flexible birth control used to prevent pregnancy.

Tofacitinib is indicated for the treatment of adult patients with severely active ulcerative colitis, severely active rheumatoid arthritis (RA), or psoriatic arthritis (PsA).

Transform Oncology Care uses results of broad-panel gene sequencing tests to help oncologists identify appropriate treatment regimens based on their patients clinical and genetic profiles.

Carefully implemented order sets may encourage evidence-based or institution-specific care though the influence of provider behavior.

A combination therapy of carfilzomib, dexamethasone, and daratumumab extended progression-free survival when compared with carfilzomib and dexamethasone in patients with relapsed/refractory multiple myeloma.

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A new method of targeted radiation therapy sends alpha-emitting particles directly to stroma cells in pancreatic cancer tissue.

Amneal has begun commercialization activities for the generic versions of sildenafil for oral suspension 10 mg/ml and aminocaproic acid tablets USP, 500 mg.

Social interactions between hypothetical health care providers and patients have the power to influence a patient’s perception on the efficacy of a treatment.

Researchers showed that treating multiple myeloma cells with gamma-secretase inhibitors allowed CAR T-cells to more accurately treat cancer tumors.

The application is based on results from the phase II KEYNOTE-057 trial, which found that pembrolizumab has encouraging activity in patients with high-risk, BCG-unresponsive CIS with or without papillary tumors.

Five-day adjuvant IVIG therapy found to significantly reduce viral load in an immunocompromised patient with severe varicella.

The FDA has previously sent warning letters to other companies for illegally selling CBD products that had claimed to prevent, diagnose, mitigate, treat, or cure serious diseases, such as cancer.

The trial identified HIV-1 virus characteristics to predict treatment efficacy with a specific antibody treatment using sequence-based methods.

Researchers have identified a channel in nerve cells that may serve as a new approach to targeting Parkinson disease.

The approval was based on a phase 3 EDITION JUNIOR trial evaluating children and adolescents, aged 6 to 17 years, living with type 1 diabetes.

The tool, which works by attaching a small sensor to the patient’s inhaler, collects data on medication use and sends medication reminders, progress reports, and disease insights to the patient’s smartphone or hub.

The findings suggest that biologics can be used for those with elderly-onset rheumatoid arthritis (RA) as effectively as for those with young-onset RA.

The FDA approved elexacaftor/tezacaftor/ivacaftor (Trikafta) earlier this month based on the results of a phase 3 clinical trial.

Riluzole oral film (Exservan, Aquestive Therapeutics) has received early-action approval from the FDA for the treatment of amyotrophic lateral sclerosis.

The case study included a 45-year-old man diagnosed with stage 3 multiple myeloma who was treated with bortezomib and dexamethasone.