Jennifer Nessel, Assistant Editor

Researchers report promising activity with a novel drug that targets a key molecular driver of clear cell renal cell carcinoma in patients with metastatic disease.

Two recently approved leukemia drugs could be enlisted against treatment-resistant lung cancer.

The report enables hospital and health systems to focus their medication safety efforts over the next 2 years on these best practices.

Retail giants such as Walmart, AT&T, and Best Buy are moving into the health care space by effectively transforming their best selling assets into health care tools.

Ongoing legislative efforts to remove religious exemptions from vaccinations have led to protests by vocal anti-vaccination advocates, who claim that the bills limit the right of parents to care for their children.

Researchers perform the most comprehensive evaluation of the cardiovascular risk of type 2 diabetes drug rosignlitazone ever completed.

Smoking cessation medication varenicline does not appear to be associated with an increased risk of cardiovascular or neuropsychiatric hospitalization compared with nicotine replacement therapy.

Monotherapy with talazoparib demonstrated encouraging antitumor activity in patients with DNA damage repair mutations and docetaxel pretreated metastatic castration-resistant prostate cancer.

Patients with ulcerative colitis have an increased risk of developing colorectal cancer (CRC), are diagnosed with less advanced CRC, and are at increased risk of death from CRC.

Patients diagnosed with Crohn disease and colorectal cancer (CRC) have a higher rate of mortality than patients without Crohn disease who are also diagnosed with CRC.

In a Directions in Oncology PharmacyTM Peer Exchange series, experts explained the right time to use bevacizumab, either as a front-line therapy or at the time of disease progression.

In a Directions in Oncology Pharmacy Peer Exchange series, experts discuss the PRIMA trial and the rationale for using PARP inhibitors.

Enfortumab vedotin-ejfv in combination with the anti-PD1-therapy pembrolizumab for the treatment of patients with unresectable locally advanced or metastatic urothelial cancer who are unable to receive cisplatin-based chemotherapy in the first-line setting.

The duration of lactation was found to be a favorable glucose metabolic biomarker profile among women with a history of gestational diabetes mellitus.

Per capita health spending for 160 million Americans in employer-sponsored health plans grew by 4.4% in 2018, marking the third consecutive year of growth above 4%.

Simplici-T1 is the first study to test activation of glucokinase in patients with type 1 diabetes by evaluating daily oral TTP399 as an adjunct to insulin therapy.

New on-demand approach could aid where the absence of pharmacies, physician offices, or basic refrigeration makes it difficult to access critical medicines, daily use chemicals, and other small-molecule compounds.

Although the specialty industry brings a positive impact across quality and continuity of care initiatives, the administration of specialty drugs is highly complex with the number of new therapies and payer requirements.

The Fair Access to Cancer Treatment Act is expected to be signed by Governor Tom Wolf in the near future.

Study findings provide further basis for dietary interventions as future treatments for disorders such as multiple sclerosis.

Positive results were based on the PROSPER trial, which evaluated the overall survival of enzalutamide plus androgen deprivation therapy versus standard of care.

Top news from across the health care landscape.

Two studies published in The Lancet have developed models to examine what may happen if the World Health Organization commits to a 3-part strategy to end cervical cancer.

An awards ceremony at the Pharmapack Europe exhibition and conference in Paris recognized pioneering packaging innovations that have significantly contributed to improving user safety, ease of use, and other health care needs.

Audible prescription labels will be available in-store at more than 420 Canadian pharmacy locations, including those at Lawtons Drugs, Sobeys, Safeway, Thrifty Foods, Foodland, IGA (western Canada), and FreshCo.

Treatment with niraparib resulted in a 38% reduction in the risk of disease progression or death in the overall study population compared with placebo.

In addition to safety and tolerability, a pair of clinical studies will evaluate the drug’s efficacy and ability to slow disease progression and to improve quality of life in patients with amyotrophic lateral sclerosis.

A study found that an injection of neutralizing antibodies is associated with enhanced T cell response that specifically recognizes HIV.

Netflix has released a new American true-crime documentary centered on a pharmacist’s journey to seek justice for his son and others affected by the opioid crisis.

New technique addresses the tendency of most CAR-T therapies to provoke immune responses against healthy tissues in patients.