Gillian McGovern, Editor

Tara Spires-Jones, DPhil, FMedSci, discusses how oligomeric tau clumps inside brain synapses, pointing to indirect evidence that it may be progressing through the brain by jumping between connections.

The co-founder, chief science officer, and chairman at Longeveron discusses the findings from the phase 2a trial CLEARMIND, as well as next steps to developing the therapy Lomecel-B.

Joshua Hare describes how Lomecel-B addresses neuroinflammation, unlike other treatments which typically target amyloid disposition.

The study also found that there were no associations with increased dementia risk when anxiety resolved.

Compared with placebo, tezepelumab reduced the annual asthma exacerbation rate in multiple subpopulations and asthma-related comorbidities.

An extension of a long-acting cabotegravir study shows safety prior to and during pregnancy in cisgender women, with full results being presented at the 2024 International AIDS Conference.

The molecule can be a potential treatment that counters effects of early-life antibiotics, which can impact the gut microbiota and increase the risk of childhood atopy and asthma.

Despite the century-long period of virus evolution, 6 of the 11 primates that received a cytomegalovirus-expressed flu vaccine survived the exposure to H5N1 flu.

Studies show an increased prevalence of autism spectrum disorder in children of mothers; mouse models have shown links between maternal asthma and altered behavior and brain function.

Following President Joe Biden’s decision to step down from re-election, VP Kamala Harris has stepped into the Democratic nominee position after support and endorsements from notable delegates and the president himself.

The findings also demonstrate that body dysmorphic disorder is also associated with high levels of comorbid psychopathology, risk, and psychosocial impairment.

Study investigators surveyed nearly 200 women on their concern around period-tracking apps’ data practices, as well as whether Roe v Wade being overturned influenced their concerns.

The authors note they will continue to investigate treatments for patients with lupus as well as safe and effective methods of delivering these molecules to patients.

The authors emphasize that clinical research should focus on real-world difficulties, and pediatric asthma control should be seen as a health care priority.

Safety and efficacy findings on Lomecel-B will be presented at the upcoming 2024 Alzheimer’s Association International Conference, which will be held July 28 to August 1.

The investigators note that the high prevalence of long COVID, including in pregnant individuals, emphasizes a need for health care professionals and patients to closely monitor symptoms.

The findings demonstrate that the mG900 region plays a significant role in Type-2 helper T (Th2) cell differentiation and enhances allergic airway inflammation.

Results show that daily injections of buprenorphine over a 7-day period was safe and well-tolerated in patients who had Clinical Opioid Withdrawal Scale scores of 4 to 7.

Prevalence of dry eye is increasing drastically, especially in younger individuals, because of the current lifestyle and increased technology use.

The authors emphasize that these findings suggest a need for targeted resources that help reduce boarding and promote equitable access to care.

The authors note that the oral, at-home treatment can be a better alternative for patients by reducing inconveniences that come with the injectable and nasal administration methods.

Higher vaccination rates were associated with less prevalent asthmatic symptoms, but additional research is needed to confirm these findings.

Fish are rich in nutrients that aid in brain development, and the model can help provide more guidance for pregnant individuals when consuming seafood.

The findings show that those with higher plasma homocysteine concentrations experienced more sleep apnea events per hour compared with those with lower concentrations.

In 2 different dose groups, the majority of patients with eosinophilic esophagitis aged 1 to 11 achieved histologic remission at week 16 compared with patients treated with placebo.

The results are promising for patients with relapsed or refractory follicular lymphoma and diffuse large B-cell lymphoma, and the trial is ongoing to assess the efficacy of odronextamab in other subtypes.

However, more research is needed to effectively integrate this biomarker into individualized asthma management strategies for pediatric patients.

The findings suggest that exploring gender identity is a normal part of adolescent development for some youths.

The monotherapy is compared with the combination regimen of elotuzumab plus pomalidomide and dexamethasone in adult patients with relapsed or refractory multiple myeloma.

According to the authors, this vulnerability may stem from either sporadic occurrences of intergenerational chains of childhood abuse.