Signs of a heart attack look different in women compared with men, according to The Washington Post. Government agencies estimate that 1 in 4 women dies of heart disease in the United States, a figure that is equal to men. However, the American Heart Association calculates a higher toll for women, at 1 in 3. Coronary heart disease is the number 1 killer among both men and women in the United States. Differences in heart disease are significant between men and women. For men, the most common sign of a heart attack is chest pain. Although women also experience chest pain, they are more likely than men to have nausea, shortness of breath, dizziness, indigestion, pain in the shoulder, jaw, or back, and fatigue that can persist for days, the Post reported. Furthermore, women are more likely to have heart attacks, despite there being no coronary obstruction compared with men. According to the National Heart, Lung, and Blood Institute, in these cases, the plaque does not accumulate major blockages, but rather spreads evenly through the walls of blood vessels, resulting in “clear” tests. Research indicates that these women are at a higher risk of heart attack that results from a narrowing in the very small arteries of the heart.