Trending News: Antidepressants are Prescribed for Major Depressive Disorder, But Individual Responses Vary

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Higher diversity of intestinal microbiota at the time of neutrophil engraftment was linked to lower mortality for patients undergoing allogeneic hematopoietic cell transplantation (HCT), according to The American Journal of Managed Care. Researchers examined the relationship between microbiota composition and clinical outcomes after allogenic HCT in patients treated in 4 centers, who were divided into 2 cohorts based on geography. Their findings demonstrated evidence of microbiome disruption and lower diversity before transplantation was associated with poor survival.

The CDC has announced that a laboratory case of SARS-CoV-2, the virus that causes COVID-19, has been confirmed in an individual with no relevant travel history or exposure to patients with COVID-19, according to Contagion Live. The CDC noted that this could be the first instance of community spread of COVID-19 in the United States, but that it is also possible that the individual was exposed to a person who returned from outside the country who was infected. This case, the fifteenth in the United States, was detected by clinicians through the US public health system.

Although antidepressants are almost always prescribed for major depressive disorder, each individual responds differently to the different classes of drugs, according to HCP Live. A research team examined whether the response to antidepressants varies systematically based on individual patient differences and whether variability is linked to the severity of major depressive disorder, antidepressant class, or how recent a study was conducted. The findings indicated that although antidepressants are often used to treat major depressive disorder, symptomatic responses can vary based on the differences between individuals and the efficacies of the individual drugs vary.

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