Pharmacy Clinical Pearl of the Day: Guillain-Barre Syndrome

In its most severe form, Guillain-Barre syndrome is a medical emergency.

Clinical Pearl of the Day: Guillain-Barre Syndrome

Guillain-Barre syndrome is a rare disorder in which the body's immune system attacks the nerves.

Insight:

  • Weakness and tingling in the extremities are usually the first symptoms. These sensations can quickly spread, eventually paralyzing the entire body.
  • In its most severe form, Guillain-Barre syndrome is a medical emergency.
  • Most people with the condition must be hospitalized to receive treatment.
  • Signs and symptoms of this syndrome include prickling; pins and needles sensation; weakness in the legs and unsteady walking; difficulty with facial movements, including speaking; double vision; severe pain that may feel achy; difficulty with bladder control; rapid heart rate; low or high blood pressure; and difficulty breathing.
  • There are 3 types to this syndrome: acute inflammatory demyelinating polyradiculoneuropathy, Miller Fisher syndrome, and acute motor axonal neuropathy.
  • Treatment options for this syndrome include plasma exchange (plasmapheresis), immunoglobulin therapy, pain relievers, physical therapy, and training with adaptive devices. This disease has no cure.

Sources:

Guillain-Barre syndrome - Diagnosis and treatment - Mayo Clinic

guillain barre syndrome - Google Search