
Opinion|Videos|February 3, 2025
Long-Term Outcomes with VMAT2 Inhibitors
Panelists discuss how long-term open-label extension studies of VMAT2 inhibitors demonstrated sustained efficacy and tolerability of both deutetrabenazine (ARM-TD and AIM-TD extensions showing durable response over 3 years) and valbenazine (KINECT 4 showing maintained improvements through 48 weeks), with low discontinuation rates due to adverse events and no new safety signals emerging during extended treatment periods.
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Episodes in this series

Video series above is prompted by the following:
- What did the following open-label extension studies reveal about the long-term safety and efficacy of the following VMAT2 inhibitors?
- Deutetrabenazine
- Valbenazine
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