Daily Medication Pearl: Glipizide (Glucotrol)

Medication Pearl of the Day: Glipizide (Glucotrol)

Indication: Glipizide is an oral blood-glucose-lowering drug of the sulfonylurea class.

Insight:

• Dosing: The recommended starting dose is 5 mg, given before breakfast. Geriatric patients or those with liver disease may be started on 2.5 mg.
• Dosage forms: 5 mg and 10 mg
• Adverse events: Includes gastrointestinal disturbances, erythema, low blood sugars, leukopenia, hyponatremia, dizziness, and drowsiness.
• Mechanism of action: Glipizide stimulates the beta cells of the pancreas to produce more insulin in the body.
• Manufacturer: Pfizer

Sources:

label (fda.gov)

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