Article

Daily Medication Pearl: Dantrolene Sodium (Ryanodex)

Ryanodex is a skeletal muscle relaxant indicated for the treatment of malignant hyperthermia in conjunction with appropriate supportive measures.

Ryanodex is a skeletal muscle relaxant indicated for the treatment of malignant hyperthermia in conjunction with appropriate supportive measures in patients with a high risk.

Insight:

Dosing: Administer by intravenous push at a minimum of 1 mg/kg.

Dosage forms: For injectable suspension 250 mg of lyophilized powder in a single-dose vial for reconstitution.

Adverse events: Administration to conscious subjects is associated with loss of grip strength and weakness in the legs, drowsiness, and dizziness.

Mechanism of action: The addition of dantrolene to the triggered malignant hyperthermic muscle cell may reestablish a normal level of ionized calcium in the myoplasm.

Manufacturer: Eagle Pharmaceuticals

Source

Approval [Rx ONLY] (ryanodex.com)

Newsletter

Stay informed on drug updates, treatment guidelines, and pharmacy practice trends—subscribe to Pharmacy Times for weekly clinical insights.

Related Videos
Asthma COPD Breath Nebulizer And Mask Given By Doctor Or Nurse - Image credit: Angelov | stock.adobe.com
Image credit:  Artur | stock.adobe.com
Cardiovascular disease doctor or cardiologist holding red heart in clinic or hospital exam room office for csr professional medical service, cardiology health care and world heart health day concept - Image credit: Chinnapong | stock.adobe.com
Image credit:  kitsawet | stock.adobe.com
Inflammation concept, inflammated human tissues 3d rendering - Image credit: picture-waterfall | stock.adobe.com