Videos

4 experts are featured in this series.

Panelists discuss how pharmacists play a crucial role in toxicity management and monitoring for CDK4/6 inhibitors (including proper QTc calculations, lab monitoring thresholds, and diarrhea mitigation strategies), how they incorporate NCCN guideline recommendations into clinical practice while identifying patients who might fall through the cracks (especially those not receiving chemotherapy), and how they consider sequencing CDK4/6 inhibitors based on postMONARCH trial data for patients with soft progression or low tumor burden without actionable mutations.

4 experts are featured in this series.

Panelists discuss how treatment selection between CDK4/6 inhibitors in early-stage breast cancer is primarily driven by trial eligibility criteria with abemaciclib being preferred when qualified, while in metastatic settings ribociclib is often favored due to overall survival data, and how adverse event profiles differ significantly among the 3 agents (neutropenia with palbociclib/ribociclib, QTc prolongation and drug interactions with ribociclib, and early-onset diarrhea with abemaciclib that typically improves with supportive care management).

3 experts in this video

Panelists discuss how IV administration of immune checkpoint inhibitors creates operational challenges, including infusion chair bottlenecks, complex scheduling, venous access difficulties, and time burdens for patients, while subcutaneous formulations offer potential solutions through simplified delivery, reduced infusion center strain, and improved patient convenience.

A panelist discusses how pharmacists can optimize shingles vaccine uptake by addressing cost barriers through insurance coverage, ensuring consistent vaccine recommendations across all health care touchpoints, and using a presumptive approach that assumes patients want protection rather than asking if they want a vaccine.

4 experts are featured in this series.

Panelists discuss how CDK4/6 inhibitors can be considered for patients with visceral crisis based on limited data from the RIGHT Choice trial (though historically chemotherapy has been preferred), and how the number of positive lymph nodes in early-stage breast cancer drives treatment selection based on the specific inclusion criteria from the monarchE and NATALEE trials, with dual-eligible patients requiring consideration adverse effect profiles and patient-specific factors.

4 experts are featured in this series.

Panelists discuss how FDA-approved CDK4/6 inhibitors are used in early breast cancer (abemaciclib and ribociclib with different trial designs and dosing regimens) and metastatic breast cancer (palbociclib, ribociclib, and abemaciclib showing approximately 2-year progression-free survival advantages in various combination therapies).

A panelist discusses how pharmacists can address vaccine hesitancy by collaborating with prescribers who recommend against vaccination through education and in-services, and by reframing patients’ concerns about being “too young or healthy” as opportunities to build robust immunity while their immune system is strong.