Investigators found that the therapeutic mechanism for bezlotoxumab, the only FDA-approved anti-TcdB antibody, is sensitive to escaping mutations in some bacterial strains.
Hypertension is a risk factor for cognitive decline and dementia in older adults.
Trilaciclib (Cosela) is indicated to reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving certain types of chemotherapy for extensive-stage small cell lung cancer.
Study presented at the American Diabetes Association (ADA) 81st Scientific Sessions shows meaningful outcomes for people with diabetes who use the FreeStyle Libre system.
Data show diabetes patients not taking medication experienced longer hospitalization and recovery from the coronavirus.
Too much bile acids can lead to damage in the cell membranes and can cause cell death and inflammation.
Initial data show that children presented with higher acuity in 2020 compared to the previous year.
Studies show that an increased life expectancy is attributable to growth in gross domestic product, increases in the average years of school, and other social factors.
Antiviral medications, including Acyclovir, famciclovir, and valacyclovir, are effective if taken as soon as the diagnosis and can shorten the duration of the infection while improving symptoms.
Novel treatments and recent data about new drugs were presented at the first conference of Advanced Topics for Oncology Pharmacy Professionals (ATOPP).
June 27 is National HIV Testing Day, so Pharmacy Times interviewed Warren O, a person living with HIV for 11 years who has first-hand experience with HIV stigma, on his perspective on the critical role of testing all sexually active individuals who may be at risk for HIV.
The small-molecule inhibitors of the SOX 11 oncogene showed promise both as single agents and in combination with ibrutinib.
Improvements in glycemic control were seen as early as 3 months after program implementation and were sustained up to a year with continued program engagement.
The objective of the study was to determine the impact of telemedicine consultations in the context of the COVID-19 pandemic on the glycemic control of patients at an endocrinology clinic.
Researchers observed improvements in total cholesterol, low-density lipoprotein, triglycerides, and serum gamma glutamyl transferase among patients both with and without diabetes.
Myokine cathepsin B, brain-derived neurotrophic factor, and klotho were all found to be influential in delaying the progression of Alzheimer disease.
Although most vaccines are administered during infancy and childhood, it is important for people in all stages of their life to continue protection efforts from eradicated and new diseases.
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The investigators conducted a systematic review of the existing literature using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to evaluate the efficacy of dietary supplements and alternative therapies for weight loss in participants aged 18 and older.
Azacitidine (Onureg) was approved by the FDA in September 2020 as a maintenance therapy for acute myeloid leukemia.
Panelists also recommended the use of bezlotoxumab as a co-intervention with standard of care antibiotics in patients with a recurrent C. diff infection within the past 6 months.
Investigators observed improvements in inflammation of the cornea and ocular itching among patients receiving Verkazia in both trials.
Ribociclib was found to prolong overall survival and improve post-progression outcomes in patients with HR-positive/HER2−negative advanced breast cancer, particularly among younger patients with a significant unmet need.
Results from the LOTIS-2 and LOTIS-3 trials show durable responses and a manageable toxicity profile among patients with both diffuse large B-cell lymphoma and mantle cell lymphoma treated with loncastuximab tesirine-lpyl (Zynlonta).
Further, the ISCs reside in a series of regularly folded valleys of the gut, which the researchers call crypts.
Individuals with diabetes, and other related underlying health conditions, are being hospitalized 6 times more often and are 12 times more likely to die of COVID-19 than those without diabetes.
The researchers noted that during high-risk pregnancies, special monitoring and care throughout the pregnancy is mandatory.
Community pharmacy teams can help reduce hospitalizations through the provision of medication reconciliation, which adjudicates discrepancies such as therapeutic omissions, duplications, dosing errors, drug interactions, and unintentional therapeutic changes.
Investigators found that a single initial dose may be sufficient for patients with prior infection.
The research team discovered that community pharmacists, as a skilled clinical workforce, could positively contribute to the future of COVID-19 vaccination programs by continuing to be active in COVID-19 vaccination campaigns.
