CLINICAL ROLE -
Tardive Dyskinesia Drug Approval Illustrates Efficient Trial Design
FDA approval of valbenazine (Ingrezza) for the iatrogenic movement disorder tardive dyskinesia shows impact of a well-executed development program.
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Improving Glycemic Control in Type 2 Diabetes Mellitus
Most experts recommend adding basal insulin, but basalization has its limits controlling glucose in type 2 diabetes.
Novel Test Can Detect Latent HIV-Infected Cells
The TZA test is faster, more cost-effective, and less labor-intensive than the current test for finding dormant HIV cells.
Ritalin Poses Cognitive Risks to Those Without ADHD
Female rats observed to be especially susceptible to methylphenidate-related behavioral changes.
First-Line Biologic Therapy Not Cost-Effective in Rheumatoid Arthritis Patients
Initiating biologics before triple therapy increases costs and provides minimal incremental benefit.
Tumor Suppression Achieved Through Enzyme Manipulation
An experimental drug reactivated an enzyme to elicit tumor suppression.
Head-to-Head Study Compares Healthcare Costs of Anticoagulants
Dabigatran etexilate mesylate (Pradaxa) may result in lower costs compared with other novel oral anticoagulants.
Cost-Effective Treatment Approaches to Rheumatoid Arthritis
Switching from DMARDs to first-line biologics may not be the optimal treatment for RA.
Novel Treatment Inhibits Tumor Growth
Targeting PP2A enzyme shows promise treating lung cancer.
New Platform Provides Resources for Multiple Sclerosis Patients and Caregivers
GatherMS aims to fill the resource knowledge gap in the MS landscape.
In-Hospital COPD Deaths Plummet by 62% Between 2005 and 2014
Women accounted for most of the hospitalization and in-hospital deaths.
Lowering the Risk of Diabetic Ketoacidosis in Young Patients
Patients who were seen at an emergency department had an increased likelihood of diabetic ketoacidosis during the next 14 days.
Heart Disease Risk Greater in Patients with Severe Mental Illness
Severe mental illness may increase the risk of heart disease more than 50%.
Trending News Today: Germs from Household Pets May Stave Off Autoimmune Conditions in Humans
Top news of the day from across the health care landscape.
Trending News Today: Senate Could Soon Vote on AHCA
Top news of the day from across the healthcare landscape.
How Pharmacists Can Influence the Future of Health Care
Health care has historically been physician-patient focused, but pharmacists and patients are changing this trend.
The Role of Pharmacists Addressing the Opioid Epidemic
Pharmacists may find themselves in an ethical dilemma related to prescribing of opioids.
JMCP Special Supplement Examines Frameworks for Assessing Value of Oncology Treatments
To address escalating drug costs, health care payers increasingly are adopting benefit designs that aim to identify and pay for medications based on their value.
A Novel Approach to Applying Value-Based Contracting to Specialty Pharmacy
Outcomes-based contracting may soon play a role in the service level agreements between a specialty pharmacy provider and a manufacturer.
Moderate Alcohol Consumption Safe for Rheumatoid Arthritis Patients on Methotrexate
RA patients can consume up to 14 alcoholic beverages per week without increasing the risk of liver damage, but rates increase with increasing levels of alcohol consumption.
Opioids Unnecessarily Prescribed for Minor Injury
Brief opioid use may increase the risk of long-term use.
Study: Medicare Not Likely to Benefit from Drug Rebates
Drug rebates may result in more beneficiaries reaching the coverage donut hole.
HIV Combination Treatment Met Primary Endpoints in Four Late-Stage Trials
Gilead plans to file for approval of novel HIV drug in the United States and Europe this year.
Multiple Sclerosis Patient Treated with Ocrelizumab Develops Severe Brain Infection
Patient with MS was previously treated for 3 years with natalizumab, a known trigger of progressive multifocal leukoencephalopathy.
Intestinal Bacteria Could Alter Blood Vessel Formation in the Brain
Malformed blood vessels in the brain can lead to stroke or epilepsy.
Footwear Guidelines Desperately Needed to Prevent Diabetes Complications
There are no guidelines to help physicians choose insole stiffness for patients with diabetes.
Spinal Nerve Loss May Not Contribute to Multiple Sclerosis Disability
Synaptic loss in the spinal cord could lead to disability in patients with multiple sclerosis.
Novel Strategy Enlists Implantable Devices to Target Residual Ovarian Tumors
Continuous low-dose cisplatin through an implantable device could be a therapeutic option in for patients with ovarian cancer.
Trending News Today: Patients Struggling to Manage COPD Drug Costs
Trending News Today: States Begin Efforts to Preserve ACA Benefits
