Broadly Neutralizing Antibodies Combination May Suppress HIV Without Antiretroviral Therapy
October 19th 2018A combination of next generation broadly neutralizing antibodies might be able to achieve long-term viral suppression of HIV without the need for a daily antiretroviral pill, according to recently published research.
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Olaparib Granted Orphan Drug Designation for Treatment of Pancreatic Cancer
October 18th 2018The investigational therapy olaparib (Lynparza, AstraZeneca and Merck) has been granted Orphan Drug Designation (ODD) by the FDA for the treatment of pancreatic cancer, according to an AstraZeneca press release.
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Combining Anti-HIV Antibodies May Suppress Virus Without Antiretroviral Therapy
October 18th 2018Broadly neutralizing antibodies have one key advantage over antiretroviral therapy: they have a longer half-life and thus don’t require the daily, lifelong dosing regimen currently required of ART users.
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CMS Officials Announce Plan to Require Price Transparency in Prescription Drug TV Ads
October 17th 2018Officials with the Centers for Medicare & Medicaid Services this week proposed requiring drug manufacturers to include prices in direct-to-consumer television advertisements for prescription drugs.
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Positive Topline Results Shown for Dupilumab in Phase 3 Trials in Patients with CRSwNP
October 17th 2018A pair of pivotal Phase 3 placebo-controlled trials that evaluated dupilumab (Dupixent, Sanofi and Regeneron) for adults with inadequately-controlled chronic rhinosinusitis with nasal polyps met all primary and secondary endpoints.
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Treatment for HER2-Negative Breast Cancer with Germline BRCA Mutation Granted FDA Approval
October 16th 2018Talazoparib, a poly ADP-ribose polymerase (PARP) inhibitor, is indicated for patients with known deleterious or suspected deleterious gBRCA-mutated breast cancer who are selected for the therapy based on an FDA-approved companion diagnostic.
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