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Interactive Case Studies: May 2023
Cases address gastrointestinal issues and alcohol abuse.
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Pharmacoscopy Platform Creates Automated, Personalized Selection of Treatment Options for Patients With Multiple Myeloma
Multiple myeloma treatment selection is critical due to the potential for developing treatment resistance over time to the currently prescribed drugs.
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Incidence of C. diff Infection Increased Significantly in Some Countries During the Pandemic
In Greece, the stark increase in Clostridioides difficile (C. diff) incidence cannot be explained by a rise of antimicrobial use during the pandemic.
Phase 2 Trial Results Show Efficacy, Safety for Treatment of Acute Cannabinoid Intoxication in the Emergency Department Setting
With no treatments currently FDA approved, patients arrive at the hospital with no options for treatment beside waiting for the intoxication to pass.
5-Year Follow-Up Studies Support B/F/TAF Regimen As Long-lasting, Effective Treatment for Patients With HIV-1
Bictegravir/emtricitabine/ tenofovir alafenamide tablets (B/F/TAF) provides long-term virologic suppression for nearly 100% of patients.
Phase 2a Trial Showed Peresolimab Reduced Joint Swelling, Tenderness in Patients With Rheumatoid Arthritis
This is the first clinical evidence to show that stimulating the programmed cell death protein 1 (PD1) inhibitory pathway is beneficial for rheumatologic disease.
Oncology Pharmacists Connect Meeting Promises Focus on Changing Treatment Paradigms, Implementation Challenges for Pharmacists
Program Chair Ryan Haumschild, PharmD, MS, MBA, discussed what attendees can look forward to at the inaugural Oncology Pharmacists Connect meeting.
Counsel Patients On the Range of Treatments for Depression
Patients with depression require long-term treatment and supportive care, either with medications or non-pharmaceutical options.
How the Decentralization of Clinical Trials Can Transform Health Care
Decentralization has already been shown to streamline clinical trials, but it also has the potential to improve the broader health care ecosystem.
Migraine: Much Progress Made, Significantly More Needed
Although an established standard of care for migraine prophylaxis exists, the current protocol is not without significant shortcomings.
Study: Mifepristone Does Not Statistically Improve Symptoms of Chronic PTSD in Male Veterans
The steroid could be more effective for veterans with post-traumatic stress disorder who do not have a history of traumatic brain injury.
Five Trends Transforming Pharmacies into Wellness Centers of the Future
With so many radical developments in medicine and technology unfolding at once, the role and potential of the pharmacy as we know it is evolving at breakneck speed.
Overweight, Obese BMI Associated With Increased Risk of Gastrointestinal Cancer
Overweight or obesity between middle and later adulthood had a statistically significant risk for noncolorectal gastrointestinal cancer.
Medication Acquisition Programs Can Improve Access to Treatment
Research has shown these programs can increase the number of patients who can access targeted treatments.
FDA Approves Pfizer’s Paxlovid for Treatment of COVID-19 in Adults
This marks the fourth drug, and first oral antiviral pill, approved by the FDA to treat adults with mild-to-moderate COVID-19.
FDA Approves Celltrion’s Yuflyma as Humira Biosimilar for 8 Disease States
It is the second anti-TNFα biosimilar approved for use in the US.
Safety, Savings Start With Medication History
Technicians should take advantage of opportunities to work at a higher level of practice, build their careers.
Sublingual Vaccine Shows Efficacy in Preventing Recurrent UTIs, Helping to Eliminate Need for Antibiotics
Women with recurrent urinary tract infections (UTIs) are often on and off antibiotics for years, and even decades, as the only treatment available in health systems for treating UTIs.
FDA Approves Xacduro for Intravenous Use in Individuals With HAI Acinetobacter Infections
Acinetobacter are gram-negative human pathogens that infect individuals who are critically ill, which can result in severe pneumonia and bloodstream infections.
Does Intermittent Fasting Work?
Eating regimen shows many health benefits, but the diet may not be appropriate for all patients.
Semaglutide With Lifestyle Interventions Shows Benefits for Adolescents With Obesity
The use of semaglutide for adolescents was included in recent pediatric guidelines, though there are few studies assessing the drug in this patient population.
Low Income Status Increases Telehealth Usage for Racial, Ethnic Minorities
Hispanic communities are more likely to use telehealth services, whereas non-Hispanic Black individuals continue to show telehealth inequities.
Significant Weight Loss Associated With Incident Lung Cancer Diagnosis
Weight loss that began as far as 2 years before a lung cancer diagnosis was associated with a risk of cancer.
Targeting a Newly Identified Gene in the Brain May Reduce Anxiety
Anxiety disorders create social and economic burdens as the availability of effective anxiolytic treatments are low.
Study: Women Identifying as Lesbian, Bisexual More Likely to Have Worse Cardiovascular Health
Sexual minority populations disproportionately suffer from mental health conditions as well, which could partially impact cardiovascular health, a recent study indicates.
Biosimilar Infliximab-dyyb Demonstrates Same Effectiveness as Remicade in Pediatric Patients
In a single-center study, investigators reviewed charts of 25 children with inflammatory bowel disease transitioning from infliximab to the biosimilar infliximab-dyyb for maintenance.
Study: Promoting Housing Stability Can Support HIV Care, Viral Suppression
Structural inequalities that contribute to HIV acquisition are known to also contribute to housing stability, and this was apparent in findings regarding race and ethnicity.
Dupilumab Is the First Investigational Biologic to Significantly Improve Lung Function in Patients With COPD
The treatment improved lung function at 12 weeks and quality of life at 4 weeks.
FDA Approves Braeburn’s Brixadi Injection to Treat Moderate-to-Severe Opioid Use Disorder
The drug is available in 2 formulations, including a weekly injection with a lower dose than previously available as well as a monthly injection.
BONUS: American Association of Pharmacy Technicians Convention 2023
Pharmacy Times spoke with 2 presenters at the American Association of Pharmacy Technicians Convention 2023, which covered Wellbutrin and opioid use disorder medication.
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