Pre-exposure prophylaxis (PrEP) is effective at preventing sexual transmission of HIV, but access is limited for people with low income. The California PrEP Assistance Program (PrEP-AP), established to remove financial and structural barriers to PrEP access, had positive but uneven results. More information was shared at the International AIDS Society (IAS) AIDS 2020 Virtual Sessions.

PrEP-AP is intended to lower out-of-pocket costs for both uninsured and insured people who are eligible for PrEP services such as laboratory tests.The program also enables access to general sexually transmitted infection treatment and wellness. PrEP-AP supplements PrEP medication access provided through manufacturer assistance programs in addition to covering the provision of post-exposure prophylaxis (PEP).

From April 2018-November 2019, active enrollment increased to more than 3,000 people. Among these people, 58% were uninsured, 38% had commercial insurance, and 4% had Medicare.

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