Asthma

Sanofi recently announced that the FDA has accepted the supplemental Biologics License Application (sBLA) of dupilumab (Dupixent) for the maintenance treatment of asthma.

In comparing environmental intervention costs with those of health care utilization, costs are reduced further with environmental intervention.

QVAR RediHaler is now commercially available to patients by prescription in 40 mcg and 80 mcg strengths.

A new tool that can measure cell strength 100 times faster than current methods may optimize drug development for several diseases.

Up to 80% of women experience gastro-esophageal reflux disease during pregnancy.

Tiotropiumis is an inhaled anticholinergic bronchodilator approved by the FDA for long-term use in patients with asthma and COPD.

The gasdermin B gene may increase cell death and inflammation in the airways associated with asthma.

Children with asthma who receive a combination of telemedicine support and school-based medication therapy may be less likely to need an asthma-related emergency room or hospital visit.

Excess weight may exacerbate asthma symptoms without affecting the efficacy of inhaled corticosteroids.

Top articles of the week from The American Journal of Pharmacy Benefits.

The results of all trials showed that the use of LABA with ICS does not significantly increase the risk of serious asthma outcomes compared to ICS alone.

A combination of long-acting beta agonists and inhaled corticosteroids may not increase mortality risk for patients with asthma.

Glycopyrrolate inhalation solution is the first nebulized long-acting muscarinic antagonist for the treatment of chronic obstructive pulmonary disease.

Hay fever and asthma are dependent on allergens that stimulate the immunoglobulin E pathway, which is not the case with atopic dermatitis.

Between 10% and 20% of students in kindergarten through high school have chronic illness.

An infant’s sex-specific gut microbiome following maternal asthma during pregnancy may influence their risk of developing childhood asthma.

Chronic obstructive pulmonary disease (COPD)—irreversible—requires long-term adherence to pharmacotherapies for best outcomes.

Benralizumab is a monoclonal antibody that causes natural killer immune cells to reduce eosinophils.

Benralizumab (Fasenra) demonstrates the ability to significantly deplete eosinophils and could reduce the need for oral steroid use.

The same genes may influence asthma, hay fever, and eczema risk.

Officials with the FDA have approved benralizumab (Fasenra, AstraZeneca) for the add-on maintenance treatment of patients with severe eosinophilic asthma aged 12 years and older.

Nucala is an interleukin-5 antagonist under consideration as an add-on maintenance therapy for certain patients with chronic obstructive pulmonary disease.

High-dose omega-3 fatty acids during the third trimester of pregnancy could prevent respiratory problems.