Matt Hoffman

A final vote that assessed whether the findings from the EMERGE trial served as primary evidence for the efficacy of aducanumab in Alzheimer disease was 10–0 that the trial did not provide evidence.

The use of benzodiazepines and related z-drugs was found to be associated with a modest increase in the risk of Alzheimer disease in a case-control trial.

Positive topline results from Study 201, a phase 2 study of BAN2401, an investigational Alzheimer Disease (AD) therapy, have been announced by Eisai Co. and Biogen.

Newly published findings from the PIONEER 1 phase 3a trial show that once-daily once-daily oral semaglutide was associated with significant reductions in blood sugar in adults with type 2 diabetes.

A study of another such program—Healthy MOMs, or Mothers on the Move—has shown significant improvements in dietary practices and the incidence of depressive symptoms in Latina mothers at risk for type 2 diabetes.

New data show an association between potentially inappropriate prescribing practices and higher risk of all-cause mortality, and both fatal and non-fatal overdose.

While normally a diabetes diagnosis requires multiple sample confirmations from blood work of elevated hemoglobin A1C (HbA1C) or glucose, new data has shown that a single-sample confirmatory diagnosis of diabetes may be possible.

As the age of technology continues to blossom, people are spending upwards of 10 hours per day looking at screens—4 hours longer than recommended by physicians.

Those with hypertension had roughly 2.5 times more inpatient costs, almost twice the outpatient cost, and roughly triple the prescription medication cost annually.

Allergan has issued a voluntary recall in the United States for a single lot of its norethindrone acetate and ethinyl estradiol capsules and ferrous fumarate capsules (Taytulla) physician sample packs.

The FDA has granted Harmony Biosciences a Breakthrough Therapy designation for pitolisant, an investigational therapy for the treatment of cataplexy in patients with narcolepsy.

After a hospitalization, age is positively associated with the likelihood of receiving an opioid prescription.

More US adults believe that it is easy to get access to opioids for unlawful use, with millennials believing this more so than baby boomers.

NRX-101 is the first drug regimen designed to treat severe bipolar depression and acute suicidal ideation and behavior.

Risankizumab shows promise as an important treatment option for people living with plaque psoriasis.

Officials with the FDA have approved fostamatinib disodium hexahydrate (Tavalisse, Rigel) for the treatment of thrombocytopenia in adults with chronic immune thrombocytopenia (ITP) who have had an insufficient response to a previous treatment

The approval is the first of its kind for a reversal agent of a novel oral anticoagulant (NOAC).

Officials with the FDA have accepted a new drug application (NDA) for Alkermes once-daily, oral, investigative major depressive disorder (MDD) therapy, ALKS 5461, intended for use in patients with an inadequate response to standard antidepressant treatment.

Mandatory recall ordered for all food products containing powdered kratom manufactured, processed, packed, or held by Triangle Pharmanaturals LLC, due to several containing salmonella.

Hydroxyurea tablets previously received priority review and orphan drug designations from the FDA.

In comparing environmental intervention costs with those of health care utilization, costs are reduced further with environmental intervention.

Rituximab (Rituxan) sparked remission among patients with pemphigus vulgaris.

A CRISPR gene-editing method has the ability to correct 3000 mutations that lead to Duchenne muscular dystrophy.

Ubrogepant had a more significant reduction of pain and migraine-associated symptoms within 2 hours of the initial dose than placebo.

Ferumoxytol (Feraheme) treats adult patients with iron deficiency anemia who have an intolerance or unsatisfactory response to oral iron.

Combination antiretroviral therapy found to elevate the risk of heart attack and adverse effects on the cardiovascular system.

Tenofovir disoproxil fumarate tablets treat HIV-1 infection in adults and pediatric patients ages 12 years and older.

Novel HIV test combines the convenience of the saliva test with the reliability of the blood test.

CAM2038 would have been the first and only injectable for opioid use disorder that can be administered by health care professionals from the start of a patient's treatment.

Greater risk of stillbirths, emergency Caesarean sections, and infant mortality found to be associated with both type 1 and type 2 diabetes.