Specialty Pharmacy

The FDA has granted accelerated approval to pemigatinib (Pemazyre, Incyte Corporation) as the first treatment for adults with certain types of previously treated, advanced cholangiocarcinoma.

This approval is a part of the first Project Orbis partnership between the FDA, Health Sciences Authority, and Swissmedic.

A protein, known as FOXO1, plays a critical role in heart damage resulting from treatment with the chemotherapy drug anthracycline.

N95 respirators can be decontaminated effectively and maintain functional integrity for up to 3 uses, according to a study by the National Institutes of Health (NIH).

Pharmacists are a rich resource, not only in the management of colorectal cancer, but in every aspect of health care.

The clinical practice update incorporates emerging evidence and available guidance for patients with IBD.

Additionally, this treatment gradually reduced the need for prophylactic FVII use, suggesting an effective control of bleeding that leads to a sustained clinical benefit in patients who received the highest doses of AAV5-hFVIII-SQ.

The combination of olaparib plus bevacizumab lead to a potentially meaningful improvement in progression-free survival versus olaparib alone in women with BRCA-mutated newly diagnosed ovarian cancer.

In a new study, researchers present their findings of a signaling pathway that could be used in patients with triple-negative breast cancer (TNBC) to enhance therapies in the future.

The JAVELIN trial is a randomized, open-label, phase 3 trial comparing avelumab in combination with chemotherapy versus chemotherapy alone.

The addition of pazoparib to gemcitabine enhances anti-tumor activity, particularly for patients with platinum-resistant disease who derived the most benefit from combination therapy, even in the setting of receiving prior bevacizumab.

A new study investigated the molecular impact of the cancer-killing PARP-1 inhibitor (PARPi) binding to PARP-1 and found that the drug can be structurally modified to increase its power to kill tumor cells.

The results of this study resonate other results, suggesting that 3D mammograms are more accurate than 2D mammograms and may help 3D mammography become part of routine breast cancer screening.

Approximately 1 in 40 postmenopausal women diagnosed with breast cancer before the age of 65 had a mutation linked to cancer in the BRCA1 or BRCA2 gene, according to an analysis of data from the Women’s Health Initiative (WHI).

The kinase inhibitor selumetinib was approved for the treatment of pediatric patients aged 2 years and older with neurofibromatosis type 1 who have symptomatic, inoperable plexiform neurofibromas.

Purdue University’s College of Pharmacy is granting early graduation to 144 students to help cover a potential shortage of pharmacists during the coronavirus disease 2019 pandemic.

Although testing and vaccination for the human papillomavirus have decreased the number of cervical cancer deaths, the disease remains the fourth most common cancer type in women.

Demcizumab is a DLL4-targeted lgG2 humanized monoclonal antibody and a potent inhibitor of the Notch pathway.

COA released a statement explaining that it fundamentally opposes home infusion of chemotherapy, cancer immunotherapy, and cancer treatment supportive drugs due to concerns regarding the safety of patients in such an environment.

Every pharmacy within the Guardian Pharmacy Service network has their own disaster contingency plan in place so that they are supported in an emergency, such as the coronavirus disease 2019 pandemic.

A case study of a patient in Wuhan, China suggests that the immunosuppressant tocilizumab may be an effective coronavirus disease 2019 treatment for patients with multiple myeloma and other blood cancers.

By mining a vast trove of genetic data, researchers are enhancing physicians’ ability to treat cancer, predict patient outcomes, and determine which treatment will work best for individual patients.

FDA updates guidelines after man who recently recovered from COVID-19 was told that he could not donate blood for 12 months because he takes Truvada as a pre-exposure prophylaxis treatment.

The FDA has approved encorafenib in combination with cetuximab for the treatment of adult patients with metastatic colorectal cancer with a BRAF V600E mutation after prior therapy.

Consuming a diet high in fiber was linked with a reduced incidence of breast cancer in an evaluation of all relevant studies, according to findings published in CANCER.

Cervical cancer screening rates in Japan were significantly affected in the years following the devastating Great East Japan Earthquake of 2011, suggesting that disasters can affect cervical cancer screening for years.

Directions in Pharmacy® is a full-day regional conference for community and health-system pharmacists.

COVID-19 has caused major upheavals across the country and pharmacy schools are no exception, as many institutions have been closed, causing professors and students to seek out innovative ways to complete their coursework for the semester.