Hospital

Precision medicine is rooted in the reality that the way patients respond to treatment is heavily affected by their individual genetic variability, their complex biology, and external factors.

Since the 2018 guideline’s publication, additional non-statin therapies such as bempedoic acid, evinacumab, and inclisiran, have been approved by the FDA for the management of hypercholesterolemia.

Diagnosing risk of frailty in patients hospitalized with heart failure is a safe and effective means of improving patient management.

Treatment-emergent adverse events were reported in a similar proportion of participants with recurrent Clostridioides difficile infection, both with and without immunocompromising conditions.

Approximately 56.6% of young adults with advanced heart disease prefer to be involved in end-of-life decisions if they were very ill, with nearly all patients saying that they would also like their parents to be involved.

Investigators of the phase 2 study also found a comparable reactogenicity to the individual influenza and COVID-19 vaccines from Novavax or authorized vaccine comparators.

Patients with HIV were no less likely to show a worse clinical presentation following tecovirimat treatment.

Brexpiprazole was associated with a statistically and clinically meaningful improvement in agitative behaviors caused by dementia compared to placebo.

Lili Wang, MD, PhD, discusses her research investigating how METTL3 regulates RNA splicing dysregulation and contributes to CLL growth.

Study shows that the nervous system of individuals experiencing post-COVID-19 fatigue is underactive in 3 key areas.

Investigators found that providing parents with a hypothetical scenario outlining why they should immunize their children against COVID-19 was effective in improving vaccination rates.

A new FDA policy would assess blood donor eligibility using a set of individual risk-based questions to reduce the risk of transfusion-transmitted HIV.

Health systems must address drivers of attrition, turnover.

Patients with C. difficile who received clonal bacteria populations via biotherapeutic injection were able to repopulate their microbiota with commensal bacteria.

Individualized treatments like cell and gene therapies are poised to scale rapidly over the next decade.

Josh Marsh, vice president and general manager of Sonexus Access and Patient Support at Cardinal Health, discussed how patient assistance programs are leveraging technology.

Tackling racial disparities among health care providers can help improve disparities faced by patients.

Closely monitored, decentralized trials have also been shown to improve electronic patient reported outcomes to 92% compliance, according to ObvioHealth.

A daily low-dose form of vitamin D3 was more effective on cancer mortality than intake of a monthly high-dose form, especially for adults aged 70 years and older.

A novel collaboration between the University of Pennsylvania and US Anesthesia Partners is working to drive evidence-based change in benzodiazepine use.

Study of cell exhaustion in immunotherapy-resistant tumors could significantly improve the benefits of cancer immunotherapy for patients with treatment resistant types of cancer.

Commonly, essential yet routine and time-consuming tasks, such as answering phone calls, scheduling appointments, or other administrative work, prevent health care workers from focusing on more value-added and enjoyable job functions.

The extra surveillance by a specialty pharmacy teams allows for faster initiation of therapy, earlier recognition of adverse effects, and promotes patient safety.

US Preventive Services Task Force also called for more research into how to address screening and treatment disparities faced by racial and ethnic minorities.

Importantly, Sullivan said data show that adverse events in the home infusion environment are no higher than in any other setting.

During a fireside chat, USP CEO Ronald T. Piervincenzi, PhD, and the Honorable Dr. Oh Yu-Kyoung, Minister of MFDS, Republic of Korea, discuss interruptions to the medical supply chain and the interventions used.

As patents expire, the development of biosimilars may increase, opening up new opportunities to compare efficacies of these drugs.

Naiffer Romero, MSc, MPH, discusses his work at U.S. Pharmacopeia to regulate nitrosamine impurities and ensure medication quality.

Dapagliflozin was established as the first SGLT2 inhibitor that demonstrated a mortality benefit for cardiovascular death from heart failure.

Shweta S. Namjoshi, MD, MPH, CNSC, discusses the role of the pharmacists in gastrointestinal care and the differences in care for pediatrics and adults.