The Pharmacy Times® Pharmacy Hospital Clinical Role section is a comprehensive resource for clinical news and expert insights on issues pertaining to hospital and health-system pharmacists.
July 25th 2025
Targeting BRD4 with BET inhibitors shows promise in reversing immune suppression by myeloid-derived suppressor cells in chronic lymphocytic leukemia.
PrEPVacc HIV Vaccine Trial Halted Due to Potential Inefficacy, But Oral PrEP Regimens Continue
December 18th 2023The study, which consists of 3 trials, will continue with oral PrEP regimens; however, the vaccination trials have stopped due to the unlikely chance of the vaccine showing efficacy.
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Navigating C. Diff During the COVID-19 Pandemic, The Impact of Antibiotic Usage and Surgeries
December 14th 2023Feldman details her experience with C. diff, how the COVID-19 pandemic slowed the timeline of care, and how her surgical history and the use of antibiotics played into the disease’s onset.
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Investigational Vaccine Has Non-Inferior Immune Response Compared to PCV20 for Pneumococcal Disease
December 13th 2023Clinical trial results show the immunogenicity, tolerability, and safety of V116 compared to a pneumococcal 20-valent conjugate vaccine for adults who had not previously received a pneumococcal vaccine.
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Tirzepatide Results in Superior Mean Percent Change in Body Weight for Those with Obesity
December 13th 2023In the phase 3 SURMOUNT-4 trial, investigators included individuals with at least 1 weight-related complication, including hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease.
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MAPS PBC Submits NDA to the FDA for MDMA-Assisted Therapy for PTSD
December 12th 2023An FDA approval of 3,4-Methylenedioxy-methamphetamine (MDMA)–assisted therapy would require the Drug Enforcement Administration to reschedule MDMA in acknowledgement of its medical use, making it available for prescription medical use.
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High-Risk Pediatric Patients With Antiphospholipid Syndrome Present Risk of Severe Health Issues
December 11th 2023The results found that 93% of individuals in the high-risk group presented persistently positive antiphospholipid antibodies, compared with 47% of individuals in the lower-risk group.
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Assessing Clinical Trial Efficacy vs Real-World Effectiveness in the Treatment of Multiple Myeloma
December 10th 2023The efficacy of treatments, which is the outcomes in the ideal clinical trial setting, are known to often be better than the effectiveness of those treatments, which are the outcomes of patients in the real-world setting.
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