CLINICAL ROLE -
Erin Hunter is an assistant editor at Pharmacy Times®. She is a proud alumna of the University of Massachusetts. She graduated with degrees in Journalism, Art History, and Environmental Conservation.
Machine Learning Models Can Improve Efforts to Offer Dynamic, Precise Kidney Care
Improvements in AI could change the way pharmacists and providers interact with, and care for, patients.
5 Key Sessions, Interviews at ASN 2023 Kidney Week Annual Meeting
Pharmacy Times will be at the American Society for Nephrology’s (ASN) 2023 Kidney Week Annual Meeting in Philadelphia, Pennsylvania, from November 2 to 5.
Asymptomatic Carriers of C diff Have 24-times Greater Risk for Developing C diff Compared to Noncarriers
Routine screenings for C diff on admission to the hospital could possibly prevent C diff transmission in the hospital setting.
FDA Approves Interchangeable Biosimilar Ustekinumab-auub for Inflammatory Diseases
The biosimilar, now legally available at the pharmacy level, demonstrated similar safety, purity, and potency to the reference product.
Study Data Show That Time-Restricted Eating May Be Effective for Weight Loss in Patients With Type 2 Diabetes
This “refreshing alternative” to calorie restriction does not include calorie counting, yet it is naturally associated with greater energy restriction compared to the latter.
Study Data Suggest That Cancer, Irritable Bowel Disease Are Associated With Risk of C Diff Infection
Patients who are immunocompromised generally had worse risk and severity of CDI.
Patients With Complicated Diabetes, Colorectal Cancer May Have Significant Risk of Death From Any Cause
However, uncomplicated diabetes was not significantly linked to a greater risk of all-cause mortality or death from colorectal cancer.
Data Show Rectal Administration of Fecal Microbiota for Recurrent CDI Safe, Simple for Routine Clinical Practice
With a new administration protocol created specifically for the routine clinic, infectious disease physicians can treat recurrent clostridioides difficile infection in less than 3 weeks.
New Study Heralds Phentermine-Topiramate as Most Cost-Effective Antiobesity Agent for Adolescents
Semaglutide was found to be the most effective drug for weight loss, but the benefits may not outweigh the cost associated with treatment.
FDA Approves Vamorolone for Treatment of Duchenne Muscular Dystrophy in Patients Aged 2 Years and Older
The drug’s mode of action is different than other types of corticosteroids because it’s based in the differential effects on glucocorticoid and mineralocorticoid receptors.
Combination Therapy More Than Doubles Survival in Patients With Metastatic Colorectal Cancer Compared to Standard of Care
This is the first phase 3 trial to evaluate a KRAS G12C-inhibitor plus an anti-epidermal growth factor receptor antibody for this type of colorectal cancer.
Nivolumab Combination Regimen Improved Survival of Patients with Bladder Cancer By A Third Compared to Chemotherapy Alone
The novel combination met the co-primary endpoints of progression-free survival and overall survival during the CheckMate -901 trial, also demonstrating sizeable improvement in objective response.
Additional Guidelines Around Biomarkers Could Improve Adjuvant Treatment of Early-Stage NSCLC
The fast pace of information can make it difficult to efficiently apply data to care.
Study: Women, Men Experience Different Forms of HIV-Related Stigma
Women with HIV reported higher rates of physical abuse than men with HIV, but women had more social support from family and friends.
Common Live Vaccines May Be Safe for Specific Pediatric Patients Who Are Recipients of Solid Organ Transplant
In a recent study, approximately 99% of children who received solid organ transplant and live vaccination against rubella had antibodies 1 to 3 months post-vaccination.
Novel Oral Medication Reduces Risk of Death by 76% in Patients With ALK-Positive Lung Cancer
The statistically significant and clinically meaningful improvement in disease-free survival is “practice-changing” and may represent a “paradigm shift” in treatment, according to experts.
Data Support Biktarvy Tablets for Virologic Suppression Among Patients With HIV
Biktarvy was found both effective and safe for long-term use in HIV, as well as for patients with mental health conditions.
Biosimilar Drugs Found as Clinically Effective as Reference Drugs, More Affordable
Following the results of a meta-analysis that reviewed biosimilar trial design and endpoints, investigators urge for greater biosimilar uptake initiatives.
Access Barriers to Rifaximin May Increase Risk of Hospitalization from Overt Hepatic Encephalopathy
In a recent study, 97% of patients had to wait a day before receiving their prescription, and this may worsen the risk of hospitalization.
Ocrelizumab Found to Suppress Immune Activity That Worsens Multiple Sclerosis Symptoms
A subcutaneous injection of ocrelizumab was markedly effective at suppressing brain lesions in patients with multiple sclerosis, according to data from a phase 3 trial.
Cisplatin Resistance May Be Caused by Domino Effect of Hyperactive Signals
TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of the EGFR signaling pathway.
Bacille Calmette–Guérin Vaccine May Prevent Most Common Cause of Death in Patients With HIV
Investigators suggest that the Bacille Calmette–Guérin vaccine, which prevented tuberculosis in nonhuman primates infected with SIV, can also protect against HIV.
Interventions to Improve Health Promotion for HIV Testing Should Consider Cultural Factors, Community Testing
Health promotional strategies should account for social contexts and cultural perspectives to increase the number of individuals who choose to test for HIV.
Study Finds PrEP Boosts Confidence of Having HIV Transmission-Free Sex Among At-Risk Populations
Pre-exposure prophylaxis found to provide peace of mind for patients at risk of HIV, and coupled with frequent HIV testing in the health care setting, lowers the perceived risk of contracting the disease.
Study: Pre-Exposure Prophylaxis Significantly Under-Prescribed to Prevent HIV in Eligible Patients
Primary care physicians, particularly in family medicine, offer PrEP at a significantly low rate, despite US Preventive Services Task Force recommendations.
Study: Black Children Less Likely Than White Counterparts to Receive EMS Transportation to Hospital for Asthma Episode
Investigators hope that continued research and addressing disparities can improve equitable access to asthma treatments for all pediatric patients.
The Community Pharmacy Can Leverage Trust To Improve Health Equity Outcomes
Community pharmacies are ideal locations to identify and recruit underrepresented patients for clinical trials.
A Collaborative Care Model Recognizes That the Oncology Patient’s Journey Does Not End At Remission
Within this care model, pharmacists can serve an important role in caring for patients, whether it is identifying adverse medication interactions or pushing patients to seek additional support.
Pennsylvania Hospital Shows That Community Cancer Centers Can Conduct Phase I Clinical Research
Providing clinical trials at community locations allows patients with travel restrictions to access novel treatments that are typically studied academic institutions.
Use of Antidepressants in Older Adults Linked to Driving Impairment on a Road Test
Use of antidepressants and other classes of prescription drugs can increase the risk of driving impairment compared to nonuse, so clinicians and pharmacists should review these risks with older adults.
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