Ashley Gallagher, Editor

Data from the CALIBRATE and CAPELLA trials show high rates of virologic suppression with the capsid inhibitor.

The drug combination reduced the risk of disease progression by 34% versus the standard of care in first-line metastatic castration-resistant prostate cancer, clinical trial results show.

The variants include Alpha, Beta, Gamma, Delta, and Omicron, and the laboratory results are consistent with other analyses.

But results of analysis show that the positive effects of vaccination still outweigh the potential adverse events.

The investigators identified this in 9% of relapsed cases of pediatric acute myeloid leukemia, but it also was present in primary samples.

Just 2 of 41 nutritionists interviewed reported using a validated screener, while 4 others said they use other tools, such as screening questions developed by other organizations, results show.

Those with the disorder during gestation and who were examined 2 to 7-years after delivery had a more than 3-fold increased risk for incident high blood pressure, results of the analysis show.

Results of CheckMate-9ER trial in first-line advanced renal cell carcinoma will be featured in 2 poster presentations at the American Society of Clinical Oncology 2022 Genitourinary Cancers Symposium.

Using a transgenic mouse model of Alzheimer’s disease, scientists demonstrate a definitive connection with oxidative brain damage.

The common-weight loss plan synergizes with chemotherapy to triple survival time compared with the treatment alone in rigorous mouse models of PDAC, the analysis shows.

Oral ibrexafungerp, a fungicidal oral treatment to prevent recurrent vaginal yeast infections, achieved superiority over the placebo for the primary and key secondary study endpoints.

If approved, Dipilumab will be the first biologic medicine available in the United States to treat uncontrolled moderate-to-severe AD for patients aged 6 months to 5 years.

Adversity has disproportionately hurt certain populations, including essential workers and women, the results of a new analysis show.

The calculation instrument displayed good discrimination, with a C-index of 0.72, as well as good calibration, investigators say.

New study results show that rapidly adding pounds in the first and final months of gestation likely plays a key role in the development of excess fat tissue in female children and adolescents.

Sutimlimab-jome is the only approved treatment for individuals with CAD and works by inhibiting the destruction of red blood cells.

The agency has also approved the baclofen oral suspension for Azurity Pharmaceuticals to treat individuals with other spinal cord diseases or injuries.

Monoclonal antibodies are highly effective at treating the virus, but they have often gone to the healthiest patients, instead of those over aged 65 years.

Culturally tailored patient navigation can improve underserved individuals’ health literacy, trust in the health care system, and use of cancer screening tools, study results show.

But 3 main challenges stand in the way of their adoption: patent litigation, patient and physician concerns, and rebates and reimbursements.

Investigators also found that intravenous immunoglobulins tend to be associated with increased frequency, though not significant, of serious adverse events.

Investigators say more research is needed to better define the etiological sex differences in young adults and the contributions of nontraditional risk factors.

New study results show that the drugs, which block estrogen production, are more effective for premenopausal and postmenopausal women.

Preliminary research results show that immigrants from Africa have lower rates of CVD and stroke.

Individuals who smoke cigarettes regularly and are yet otherwise healthy, without high blood pressure or type 2 diabetes, are still risking their brain health, new study results show.

Effective pre-exposure prophylaxis limits the additional price that payers should be willing to pay for the pre-exposure prophylaxis, investigators say.

Even after taking cardiovascular risks or vascular brain injury into account, the association remained, study results show.

Results from a clinical trial led by investigators at the National Cancer Institute show that 28 of 42 women with tumors generated a reaction.

Investigators find that a small protein cell glucagon-like peptide-1 (GLP-1) couples the body’s control of blood sugar and BP.

Limited empirical data from new study suggests correlations between obesity and individual SDOH, such as education level, food environment, income, and neighborhood.