Aislinn Antrim, Associate Editorial Director

Treatment with Injectafer significantly improved exercise capacity compared to placebo in a randomized clinical trial in adult patients with heart failure.

Findings presented at the American Society of Clinical Oncology (ASCO) 2023 meeting show the long-term efficacy and safety profile of larotrectinib (Vitrakvi; Bayer) in solid tumors with NTRK gene fusion.

Investigators previously reported a statistically significant improvement in radiographic progression-free survival in the full intention-to-treat population of adults with deleterious or suspected deleterious BRCA-mutated metastatic castration-resistant prostate cancer.

Structural inequalities that contribute to HIV acquisition are known to also contribute to housing stability, and this was apparent in findings regarding race and ethnicity.

The preventive effect is believed to be a result of compounds unique to cranberries called proanthocyanidins.

The risk of long COVID-19 in females in the least deprived areas was comparable to the risk of males in the most deprived areas.

Supportive nurse managers and supervisors as well as nurses’ involvement in organizational governance may help lower hospital-onset Clostridioides difficile infection in acute care hospitals.

Findings suggest that mice derived from and breastfed by immunized mothers were capable of producing anti- pneumococcal surface protein A (PspA) specific antibodies, despite having no direct exposure to PspA.

Treatment with epcoritamab-bysp showed a 61% overall response rate and a 38% complete response rate in heavily pretreated patients with R/R DLBCL.

The approval marks the first and only FDA-approved treatment for dry eye disease that directly targets tear evaporation.

Nanoparticles could improve the solubility of drugs, aid in treatment escape from the immune system, and increase the half-life of drugs in the circulatory system against viral lung infections such as influenza, coronavirus, and respiratory syncytial virus.

PCV10 protection is likely to have reduced the incidence of pneumococcal disease among all ages by between 48% and 66%.

Treatment-emergent adverse events were reported in a similar proportion of participants with recurrent Clostridioides difficile infection, both with and without immunocompromising conditions.

A new FDA policy would assess blood donor eligibility using a set of individual risk-based questions to reduce the risk of transfusion-transmitted HIV.

US Preventive Services Task Force also called for more research into how to address screening and treatment disparities faced by racial and ethnic minorities.

As patents expire, the development of biosimilars may increase, opening up new opportunities to compare efficacies of these drugs.

Evidence suggest better outcomes results when a program is responsive to the significant needs of this population.

Lack of awareness, or anosognosia, may be present up to 2 to 3 years before an Alzheimer dementia diagnosis is made.

There was a decreasing trend for new-onset atrial fibrillation incidence with higher cumulative doses of dexmedetomidine.

There are still significant unresolved issues in artificial intelligence and machine learning, which must be addressed before they can be safely and effectively used more broadly in medicine.

Mental health interventions are a critical part of the global response to HIV, with multiple potential roles for psychiatrists and other mental health professionals.

Ivacaftor is now the first and only cystic fibrosis transmembrane conductance regulator modulator approved for this age group.

In addition to 2 FDA-approved options, several clinical trials are investigating other potential treatments for immunoglobulin A nephropathy.

Pharmacists will play a growing role in the use of biosimilars and guiding patients through the switching process.

Balancing clinicians’ priorities with the needs of patients and their families is crucial to ensure access and adherence to medications.

Pharmacists play key roles in navigating prior authorizations and other limits on utilization, as well as educating and listening to patients and caregivers.

Session at the 2023 Asembia Summit notes that pharmacists play a particularly important role in the large multidisciplinary care team needed for Rett syndrome management.

The flexible 1- and 2-month dosing intervals of risperidone could help address adherence challenges common with schizophrenia treatments.

The formulation in 960 mg and 720 mg prefilled syringes delivers sustained plasma concentrations comparable to those demonstrated in studies with Abilify Maintena.

Nearly 84% of hospitals are working to prevent and mitigate burnout, with increased support and programs for individual wellness and resilience practices.