Aislinn Antrim, Managing Editor

The approach inverts missing alleles into an immune cell activating signal, which engineered T cells can then attack and destroy.

With a wide array of cannabidiol (CBD) and CBD extract products available without a prescription, pharmacists have an increasingly important role to play in counseling patients on which products may work for them and how they should be properly used.

Adverse effects, such as strange dreams, insomnia, and sleep disorders may be more likely for patients with a history of cardiovascular health issues.

Although COVID-19 tests fell by 10% during the past week, positive cases fell by a significant 12%, resulting in the ninth consecutive week of a declining national positivity rate.

With a 1-hour infusion and lower infusion volume, oritavancin could minimize health system costs to treat these infections and improve efficiency in clinical practice.

Some HIV antibody variants, which had mutations concentrated in antibody framework regions, achieved up to 37% neutralization breadth compared to 28% neutralization in the unmodified antibody.

In addition to prevention with a live attenuated vaccine, treatment options for herpes zoster can include antivirals or symptom management with corticosteroids or analgesics.

There have been 15 events of deep vein thrombosis and 22 events of pulmonary embolism reported across the European Union and United Kingdom.

Sodas have significantly high sugar levels and a lack of nutritional value, which may contribute to conditions that can lead to breast cancer.

Findings show that an inflamed environment allows clostridioides difficile to thrive in an environment that is inhospitable to competing bacteria.

Bristol Myers Squibb and bluebird bio are seeking FDA approval for ide-cel as a standard therapy for relapsed myeloma, with a decision expected by the end of March.

The investigators observed a near normal age distribution among patients with long-term COVID-19 symptoms, including children.

Compared to the placebo group, patients with diabetes who received a 54-week course of treatment had higher levels of endogenous insulin secretion with no identified safety concerns.

The oral, next-generation vascular endothelial growth factor tyrosine kinase inhibitor is the first therapy approved for this patient population following 2 or more prior systemic therapies.

Study finds cancer survivors were 42% more likely to report walking at the slowest pace and had a 24% greater risk of mobility disability compared to individuals who never had cancer.

The change in guidelines address how to assess damage to the kidneys caused by fluid loss associated with severe C. diff infection.

The potential for some people to skip the second COVID-19 vaccine dose may make more doses available to others.

The additional COVID-19 doses will provide a buffer in addition to the already procured vaccines, and will also allow experts to plan for the later part of 2021, according to a White House briefing.

When applied as a filler for soft tissue defects and voids, the regenerative tissue filler shows promise for accelerating and improving tissue restoration outcomes.

Notably, the United States has now administered the most first-shot COVID-19 vaccinations of any country, with 82.6 million.

The guidance said relaxing certain measures for vaccinated individuals may help improve COVID-19 vaccine acceptance and uptake.

Women who attended the 2 more recent screenings prior to their breast cancer diagnosis had a 50% lower incidence of their cancer being fatal within 10 years.

Study findings demonstrate the importance of interventions for multiple sclerosis therapy, such as those supporting medication adherence, adverse effect management, symptom management, and additional counseling.

New protein-based immunotherapies could stimulate patients’ immune systems without needing to engineer T cells on an individual basis.

The investigators urged continued safety measures, such as social distancing and school closures, in order to prevent more COVID-19 variant-related deaths and hospitalizations.

Investigators have found that the evolutionary sequence of insulin has become stuck at the edge of impaired production, limiting its ability to adapt to obesity and rendering most people vulnerable to type 2 diabetes.

Investigators are set to begin testing sulfasalazine and auronofin, which are FDA-approved to treat rheumatoid arthritis, in cancer cell models.

Although there have been many challenges and concerns during the pandemic, experts said there are also lessons to be learned and implemented once the pandemic is over.

Approximately 2 million doses of Johnson & Johnson's single-dose COVID-19 vaccine are ready to ship and supply is expected to sharply increase, with up to 20 million doses available by the end of March.

The vaccine has been shown to induce mucosal immunity in the nasal cavity, which may be effective in blocking transmission of SARS-CoV-2.