Using uACR as an Early Warning Signal for Kidney and Cardiovascular Risk

In this interview with Pharmacy Times, Eugene Wright, MD, discusses the importance of urine albumin-to-creatinine ratio (uACR) testing as an early indicator of kidney and cardiovascular disease risk. He explains that individuals with diabetes, hypertension, obesity, or a family history of chronic kidney disease should undergo annual screening with both uACR and estimated glomerular filtration rate (eGFR). Wright emphasizes that albuminuria is not solely a kidney issue but a marker of broader vascular dysfunction that can signal future complications. He compares uACR to a “check engine light,” highlighting its role in identifying problems before more serious disease develops. The discussion also underscores the importance of patient-provider communication, encouraging individuals to proactively ask about testing.