News|Articles|May 13, 2026

Gabapentinoid Use Is Associated With Increased Risk of Drug Poisoning, Study Finds

Author(s)Gillian McGovern, Editor, Kenneth Man, BSc, MPH, PhD

Fact checked by: Danielle Valletti, Assistant Editor, Nicole Canfora Lupo

The study authors also emphasized that close monitoring during gabapentinoid treatment is necessary, and concomitant use with opioids or benzodiazepines should be avoided.

According to the study authors of research published in PLOS Medicine, gabapentinoids, such as gabapentin, appeared to be associated with an increased risk of drug poisoning. The authors emphasize that close monitoring throughout the treatment journey is necessary for drug poisoning, particularly at the initial phase of treatment.¹