Daily Medication Pearl: Fluticasone/Salmeterol (Wixela)

Article

Wixela Inhub is indicated for the treatment of asthma in patients 4 years of age and older and maintenance treatment of patients with chronic obstructive pulmonary disease.

Medication Pearl of the Day: Fluticasone/salmeterol (Wixela)

Indication: Wixela Inhub is a combination product containing a corticosteroid and a long-acting beta2-adrenergic agonist (LABA) indicated for the treatment of asthma in patients 4 years of age and older. Maintenance treatment of airflow obstruction and reducing exacerbations in patients with chronic obstructive pulmonary disease (COPD).

Insight:

  • Dosing: For oral inhalation only. Asthma—1 inhalation of Wixela 100/50, 250/50, or 500/50 twice daily. Starting dosage is based on asthma severity. Maintenance treatment of COPD—1 inhalation of Wixela Inhub 250/50 twice daily.
  • Dosage forms: Inhaler containing a combination of fluticasone propionate (100, 250, or 500 mcg) and salmeterol (50 mcg) as a powder formulation for oral inhalation.
  • Adverse events: Upper respiratory tract infection or inflammation, pharyngitis, dysphonia, oral candidiasis, bronchitis, cough, headaches, nausea, and vomiting.
  • Mechanism of action: Fluticasone propionate is a synthetic trifluorinated corticosteroid with anti-inflammatory activity. Salmeterol is a selective long-acting beta adrenergic agonist.
  • Manufacturer: Mylan

Sources:

Related Videos
Image credit: Azee/peopleimages.com | stock.adobe.com
Pharmacy, medicine and senior woman consulting pharmacist on prescription. Healthcare, shopping and elderly female in consultation with medical worker for medication box, pills or product in store- Image credit: C Daniels/peopleimages.com | stock.adobe.com
Laboratory test tubes and solution with stethoscope background | Image Credit: Shutter2U - stock.adobe.com
Image credit: Andrea Izzotti
Inflation Reduction Act is shown using the text and the US flag - Image credit: Andrii | stock.adobe.com
Pharmacy Interior | Image Credit: Tyler Olson - stock.adobe.com
Male pharmacist selling medications at drugstore to a senior woman customer | Image Credit: Zamrznuti tonovi - stock.adobe.com
Pharmacist assists senior woman in buying medicine in pharmacy - Image credit: Drazen | stock.adobe.com
Pharmacy, medicine and senior woman consulting pharmacist on prescription. Healthcare, shopping and elderly female in consultation with medical worker for medication box, pills or product in store - Image credit: C Daniels/peopleimages.com | stock.adobe.com
Image credit: fidaolga - stock.adobe.com
© 2023 MJH Life Sciences

All rights reserved.