Daily Medication Pearl: Armodafinil (Nuvigil)

Medication Pearl of the Day: Armodafinil (Nuvigil)

Indication: Armodafinil is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD).

Insight:

• Dosing: OSA or narcolepsy 150 mg to 250 mg once a day in the morning.
• Dosage forms: Tablets 50 mg, 150 mg, 200 mg, and 250 mg.
• Adverse events: Most common adverse reactions (³5%) are headache, nausea, dizziness, and insomnia.
• Mechanism of action: Armodafinil and modafinil have wake-promoting actions similar to sympathomimetic agents, including amphetamine and methylphenidate, although their pharmacologic profile is not identical to that of the sympathomimetic amines.
• Manufacturer: Teva Pharma

Sources:

• NUVIGIL® (armodafinil) tablets (fda.gov)
• nuvigil image - Google Search