Gene Shields Lung from Toxins
Individuals may have a master gene that helps protect the lungs from pollutants, making them less susceptible to lung diseases. Johns Hopkins University researchers discovered that the gene is triggered in response to environmental hazards (eg, cigarette smoke). The gene then turns on 50 other antioxidant and pollutant-detoxifying genes to protect the lungs from developing emphysema and other conditions. In a strain of mice that is normally resistant to emphysema related to cigarette smoke, the disruption of the gene caused earlier onset and more severe emphysema.
"With this new gene and environmental interaction discovery, in the future we may be able to identify people who are genetically predisposed to developing lung diseases?not just COPD?that are caused by environmental factors," said senior researcher Shyam Biswal, PhD.
Articles in this issue
Newsletter
Stay informed on drug updates, treatment guidelines, and pharmacy practice trends—subscribe to Pharmacy Times for weekly clinical insights.
Related Articles
- Advise Patients About Self-Care Measures to Treat Mild to Moderate GI Issues
September 18th 2025
- Evaluation of Pharmacist-Driven Penicillin Allergy Reconciliation
September 17th 2025
- Pharmacists Can Apply Their Expertise to the Medical Psilocybin Act
September 16th 2025
- From Curiosity to Clinical Impact: Shremo Msdi’s Path in Pharmacy Research
September 15th 2025