Sequencing BCMA Therapies and Identifying the Right Patient: Treatment Selection and Access Considerations in Relapsed/Refractory Multiple Myeloma
ByRyan Haumschild, PharmD, MS, MBA, CPEL ,Zahra Mahmoudjafari, PharmD, MBA, BCOP, FHOPA,Al-Ola Abdallah, MD,Anjulie Quick, MD Zahra Mahmoudjafari emphasized that treatment sequencing in relapsed/refractory multiple myeloma (RRMM) must be highly individualized, taking into account prior BCMA exposure, disease burden, caregiver support, logistical factors, comorbidities, and institutional access to specific therapies such as CAR T-cell therapy, noting that while a standardized algorithm would be ideal, the complexity of the disease and evolving evidence base make a one-size-fits-all approach impractical.