A disturbed sleep cycle could have effects that lead to an increased risk of Alzheimer disease, according to MD Magazine. A 2-condition crossover study included 15 healthy young male participants in 2 standardized sedentary in-laboratory conditions in randomized order comparing normal sleep with overnight sleep loss. The exploratory study suggests that acute sleep loss results in increased blood levels of t-tau, and that these changes provide further evidence that sleep loss may have detrimental effects on brain health, even in young individuals.

Latinos are shown to be disproportionately affected by poorer quality of life and intensified disease severity, according to The American Journal of Medicine. Using data from the National Health and Nutrition Examination Survey, researchers found that Latinos have reduced psoriasis prevalence compared with white and black patients, but that psoriasis affects the US Latino population with more disease severity and a greater quality-of-life impact. The study authors wrote this association may be attributed to delayed diagnosis and this patient population is less likely to seek or receive care for the disease.

Rates of hospitalizations for serious infections among people with substance use disorders are increasing, particularly among young people, according to Contagion Live. Researchers identified hospitalizations among patients >18 years from 2012 to 2017 with a primary discharge diagnosis of selected bacterial infections, including infective endocarditis. Researchers found that the estimated rate of combination infective endocarditis and substance use disorder hospitalizations more than doubled from 1.6 to 3.6 per 100,000 people during this time period.