Specialty Pharmacy

Gilead has refined the pharmacokinetics of tenofovir disoproxil fumarate (TDF), an anchor drug in several single-tablet medications for HIV-1, to create tenofovir alafenamide (TAF). Phase II results indicate superior renal outcomes and equivalent clinical outcomes with TAF versus TDF.

Four children who recently died have tested positive for enterovirus D68, though it is not yet clear what role, if any, the virus played in their deaths.

A metaanalysis shows that levels of an antioxidative endogenous metabolic byproduct-uric acid-are correlated with disease activity in multiple sclerosis.

Officials stress that the strength of the US health care system will contain the virus.

A new metaanalysis suggests that quitting smoking, or even reducing tobacco intake, reduces the risk of dying from prostate cancer.

As the Ebola outbreak worsens, interest in therapies using recovered victims' blood grows.

Michael Nameth, RPh, MBA, chief executive officer of Aureus Health Services, discusses the major hurdles facing mid-size specialty pharmacies.

The current Ebola epidemic is causing the health care system in West Africa to collapse.

A combination of vemurafenib (Zelboraf) and experimental drug cobimetinib significantly reduces the development of secondary skin cancer.

Adding panobinostat to a combination treatment of bortezomib and dexamethasone in heavily pretreated patients boosts progression-free survival, but overall survival data are not yet mature.

In a recent phase III trial, a 3-medication regimen showed efficacy in reducing treatment-related nausea and vomiting in patients with multiple myeloma undergoing induction therapy before autologous stem cell transplant.

Obama calls for international response to prevent "humanitarian catastrophe."

A combination of Lactobacillus plantarum and a modified inulin derivative reduced expression of T-cells in mammary cancers induced in rats.

A recent metaanalysis suggests that prediabetes increases the risk of developing certain cancers, particularly in tissues located near the gastrointestinal tract.

RX-3117 maintains anti-tumor activity in cancer cell lines that are resistant to gemcitabine.

Thomas Cohn, chief strategy officer at Armada Health Care, discusses the impact of the Affordable Care Act on specialty pharmacy industry trends.

Smoking may be especially harmful to patients with irritable bowel disease.

Potential for widespread chaos and eventual collapse of hardest-hit nations without ramped-up international response.

Researchers in Japan are beginning to construct patient-centered counseling techniques for breast cancer by evaluating patient preference.

Respiratory illness now confirmed in 27 states, with significant growth expected in coming weeks.

One major challenge in breast cancer is determining which treatment will be most effective for an individual patient's tumor. With a genetic panel, the TAXSig system may help change that.

Model used to predict eventual size of Ebola outbreak outpaced by scale of current epidemic.

Protein found to play vital role in development of disease.

Camber Pharmaceuticals presents Econdisc Contracting Solutions with Customer of the Year award at the 2014 NACDS Total Store Show.

Efforts to contain the virus increase as death toll continues to rise.

Researchers find 23 new prostate cancer risk sites on the genome.

Paper also offers insight from specific case studies into the ACO-PAC Engagement Spectrum.

Much higher rate of patients in real world discontinuing high priced treatment than during clinical studies.

Disease modifying therapy maintains effects of interferon in the body for a longer duration.