Hospital

Management of marginal zone lymphoma was impacted by the COVID-19 pandemic because some treatment options can reduce B-cell-produced antibodies.

Establishing new use criteria led to an 86% reduction in the utilization of sugammadex with no appreciable impact on measured outcomes.

While the performance of nasal self-sampling rapid antigen tests for COVID-19 was found to decrease over time, adding oropharyngeal may improve its performance.

Men with chronically low testosterone levels are more likely to be hospitalized from COVID-19 than those with normal levels, but testosterone therapy could decrease this risk.

Corticosteroids are first-line therapy for gaining platelet stability but should only be used short term.

Online communities can help opioid users in remission maintain long-lasting sobriety, however the research suggests these communities should be non-drug-related.

Care Coach program offers a comprehensive set of pharmacy and counseling services to patients struggling to manage their diabetes.

NVG-111 is a humanized, tandem single-chain variable fragment ROR1 x CD3 BiTE being evaluated in relapsed/refractory chronic lymphocytic leukemia and mantle cell lymphoma.

Eflapegrastism-xnst injection (Rolvedon, Spectrum Pharmaceuticals) is indicated to lower the incidence of infection, as demonstrated by febrile neutropenia, in adult patients with non-myeloid malignancies.

The drug improves kidney function in adults with hepatorenal syndrome with rapid reduction in kidney function.

Researchers found that patients diagnosed with early-onset type 2 diabetes have a greater risk of premature death than the general population.

Prior authorizations have delayed time to treatment for patients and can directly impact clinical outcomes.

Panelists discuss pharmacist involvement in effective management, including disease burden and quality of life.

Triplet combination demonstrates a reduction in the risk of disease progression or death in individuals with previously untreated advanced intermediate- or poor-risk renal cell carcinoma.

Researchers have identified hydroquinine as a potential treatment against drug-resistant bacteria, which can cause infections with a 70% mortality rate.

Many health care systems use these products to provide similar but cheaper clinical outcomes.

Research suggests that subcutaneous insulin aspart is a cost-effective and accessible treatment option that could allow children with type 1 diabetes to avoid the ICU after a mild episode of diabetic ketoacidosis.

Therapy shows positive clinical efficacy and favorable tolerability as a monotherapy and in combination with cetuximab in heavily pretreated patients who have a KRASG12C mutation.

New research presented at ESMO Congress found that certain patients with advanced melanoma administered a combination of cemiplimab with fianlimab experienced a median progression-free survival of 2 years.

Excess drinking is a major atrial fibrillation risk factor in young people.

Researchers at the European Society for Medical Oncology Congress presented findings that show osimertinib may clinically reduce the risk of lung cancer recurrence.

Research suggests that rucaparib can increase progression-free survival by more than a year in women with advanced ovarian cancer.

Trastuzumab deruxtecan produces a confirmed objective response rate of 53.8% and 42.9% in the 5.4 mg/kg arm and 6.4 mg/kg treatment arms, respectively, among patients with HER2 mutant non-small cell lung cancer.

An estimated 31.4% of individuals with non-squamous non–small cell lung cancer treated with the combination were alive at 3 years compared to 17.3% for those on chemotherapy alone.

Results demonstrated a 64.5% confirmed objective response rate in patients treated with the investigational combination.

Ribociclib with endocrine therapy was found to increase the median overall survival of patients with HR+/HER2- advanced breast cancer with visceral metastases to nearly 5 years.

Data presented at the 2022 ESMO congress show poziotinib has high activity in both treatment-naïve and previously treated patients with non-small cell lung cancer.

Case report describes severe complications from spontaneous bladder rupture caused by herpes zoster-associated urinary retention.