Jennifer Barrett, Associate Editor

Spending for the 10 most expensive brand name combination drugs could have been reduced by an estimated $2.7 billion between 2011 and 2016 if lower-cost generics had been prescribed, according to researchers.

Researchers investigated whether heavy alcohol consumption in early life was associated with high-grade prostate cancer in adulthood.

Women who carry the BRCA1 and BRCA2 gene mutations are at an increased risk of breast and ovarian cancer, yet many women are unaware of their mutation status.

Amyotrophic lateral sclerosis and frontotemporal dementia exhibit key similarities in underlying molecular mechanisms tied to the dysfunction of RNA-binding proteins.

Substituting brand name combination drugs for lower-cost generics could have reduced spending by $925 million in 2016.

New drug could serve as a potential treatment option for patients who have shown an inadequate response to conventional disease-modifying drugs.

Improved access to uniform cancer care in rural areas could help reduce disparities seen between rural and urban patients.

Molecular link found between aging and a major genetic cause of 2 neurodegenerative disorders.

A new HIV therapy demonstrated its efficacy in reducing the virus and boosting immunity in drug-resistant patients, according to a recent published study.

Researchers uncover myelocortical multiple sclerosis, a new subtype of the disease that features neurodegeneration but lacks white matter myelin loss in the brain.

Phase 3 study results showed that the new HIV therapy ibalizumab reduced viral replication and increased immunity in drug-resistant patients.

Machine-learning technique reduces toxic treatment dosing for glioblastoma while maintaining tumor-shrinking benefits.

Nanoparticles that act as an ‘on and off’ switch could help improve the safety and efficacy of CAR T-cell therapy.

Officials with the FDA have expanded the indication of pembrolizumab (Keytruda, Merck) for patients with metastatic, non-squamous non-small cell lung cancer.

More than 4 in 10 women with asthma may develop chronic obstructive pulmonary disorder, but many risk factors are modifiable.

According to a recent study, older adults and Hispanics are less likely to receive HIV testing, indicating an urgent need for improved interventions.

Officials with the FDA have expanded the indication of pembrolizumab (Keytruda, Merck) for patients with metastatic, non-squamous non-small cell lung cancer (NSqNSCLC).

Pembrolizumab in combination with chemotherapy reduced the risk of death by half in patients with metastatic, non-squamous non-small cell lung cancer compared with chemotherapy alone.

Privately-insured patients with follicular lymphoma (FL) have nearly 2-fold better survival outcomes compared with publicly-insured or non-insured patients, according to a new study.

Interventions must address HIV testing and beliefs among both patients and providers in order to reach underserved populations.

Study evaluates the effect of multiple sclerosis treatment alemtuzumab (Lemtrada) on the B-cell component of MS.

New study finds that privately-insured patients with follicular lymphoma have better survival outcomes.

Celtaxsys’ acebilustat is the first novel anti-inflammatory molecule with the potential to both reduce pulmonary exacerbations and prolong time to first exacerbation.

With this approval, nivolumab (Opdivo) offers a new treatment option for patients with small cell lung cancer whose cancer has progressed after 2 or more prior lines of therapy.

Two new studies highlight trends in life expectancy and mortality across high-income countries, citing worsening health in the United States.

Assessment of neurofilament light chain levels offers real-time, efficient measure marker of multiple sclerosis progression.

Childhood exposure to secondhand smoke may heighten the risk of developing rheumatoid arthritis (RA) later in life, even in non-smokers, according to new research.

health care reimbursements for medications in the United States are not consistently aligned with their value or net health benefits, according to a new study.

Exposure to secondhand smoke in childhood can lead to greater risk of rheumatoid arthritis later in life, even in non-smoking adults.

A liquid biopsy test examines circulating tumor cells in blood samples of patients with prostate cancer to determine how they will respond to certain therapies.