CLINICAL ROLE -
Fun Fact: What Are Sirtfoods, and Are They Good for You?
Evidence suggests foods that activate sirtuin proteins may be beneficial for metabolic syndromes
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Low Melatonin in the Gut Can Increase Risk of Neurological Disorders
Melatonin is linked to circadian rhythm, mitochondrial function, and neuroinflammation.
Vitamin A Derivative May Have a Significant Role in Wound Healing
Vitamin A regulates stem cell differentiation to manage wound healing, although risk of tumor growth may increase if differentiation does not occur.
Table Salt Fortified With Folic Acid is A Cheap, Effective Way to Prevent Fatal Birth Defects
Fortification with folic acid may be especially beneficial in countries that do not have mandated folic acid fortification regulations.
FDA Grants Fast Track Designation to PT886 for the Treatment of Pancreatic Cancer
PT886 (Phanes Therapeutics) received fast track designation 2 years after receiving orphan drug designation by the FDA.
Community Pharmacy Can Help Solve Health Equity Challenges in Clinical Research
A lack of equity in clinical research has direct impacts on patient care and outcomes
Cranberry Supplementation Can Boost Athletic Performance During Strenuous Exercise
Cranberry extract improved speed in the 1500-meter time trial by 1.5%.
New Compound Found in Edible Mushroom May Pave the Way for Antioxidant-Based Medicines
The study represents a new era of research into mushrooms as a resource for pharmaceutical development.
Glucophage Activates the Same Pathway as Sprint Exercise to Reduce Appetite
The oral medication activates an “anti-hunger” molecule which may prevent people from overeating.
FDA Approves Expanded Indications for Spesolimab-sbzo Injection for the Treatment of Generalized Pustular Psoriasis
To date, this is the only targeted therapy indicated for the treatment of generalized pustular psoriasis.
The Care Partner Clinic Addresses Common Barriers to Care
Pharmacists at this clinic work with patients to improve medication education, affordability, and access to care.
Topical Minoxidil Improves Hair Growth in 87% of Pediatric Patients With Chemotherapy-Induced Alopecia
The FDA-approved topical and oral agent is currently indicated for adult patients with patterned alopecia.
Risankizumab Significantly Reduces Severity of Psoriasis Symptoms
Compared to placebo, risankizumab significantly reduced symptom severity for patients with moderate to severe disease.
Ovarian Function May Be Associated with Lifespan
Women who have longer ovarian function and enter menopause later in life tend to live longer, according to women’s health researcher.
Risankizumab Demonstrated Superior to Apremilast for Patients With Moderate Psoriasis
This treatment improved the severity of symptoms in patients with scalp and nail psoriasis.
Upadacitinib Can Significantly Improve Clinical Outcomes in Patients With Atopic Dermatitis
Findings originate from phase 3 data that was recently presented at the 2024 American Academy of Dermatology (AAD) Annual Meeting.
A New Study Finds That Ruxolitinib Cream 1.5% Is Effective for Most Patients With HS
The cream significantly reduced abscesses and inflammatory nodules, reaffirming its efficacy as a maintenance option for HS.
Longevity Science Does Not Only Focus on Living Longer
Health span, wealth span, advocacy, and ethics are all burgeoning topics within the field of longevity.
Navigating Research in Psychedelics: Investigators Face a Mosaic of Regulations, False Perceptions, and Therapeutic Potential
If clinical trials continue to show that psychedelics offer safe and long-lasting results, then psychedelic-assisted therapy could flourish as a treatment in the mental health space.
Secukinumab May Significantly Reduce Inflammation in Patients With Hidradenitis Suppurativa
Secukinumab affects levels of inflammatory biomarkers, and monitoring levels can help investigators understand how patients are responding to treatment.
Gestational Diabetes Mellitus Could Increase Maternal Susceptibility to Group B Streptococcus
GBS can cause transcriptional adaptations, which may increase risk of poor neonate outcomes.
FDA Questions Donanemab Efficacy for the Treatment of Alzheimer Disease
The FDA is convening a committee to discuss phase 3 data after the planned action date, which delays drug availability to patients.
Small Vessel Disease, Amyloid Pathology Can Independently Reduce Cognition in Adults With T2D
Diabetes is a known risk factor for cognitive decline and small vessel disease.
Vitamin D May Prolong ‘Honeymoon Phase’ of Type 1 Diabetes in Patients With Recent Diagnosis
Vitamin D preserved insulin-producing cells and cell function, which can reduce complications in young patients.
CAR T-Cell Therapy A2B530 Receives Orphan Drug Designation for the Treatment of Colorectal Cancer
The novel therapy is also being evaluated for the treatment of solid tumors in pancreatic and non-small cell lung cancers.
Environmental Toxin BPA Affects Gut Microbial Communities in Children
Children with normal weight had different community relationships compared to children with overweight or obesity.
Prenatal Exposure to General Anesthesia Increases Risk of Subsequent ADHD, Behavioral Disorder Diagnosis
There have been ongoing concerns about the long-term effects of prenatal exposure on neurodevelopment.
Metabolites May Predict Risk of Developing Diabetes in Patients With Sleep-Disordered Breathing
In some instances, metabolites can predict risk in patients who still have normal glucose biomarkers.
Approximately 25% of Pregnant Women Are Not Getting Enough Omega-3 Fatty Acids
Omega-3s are important during pregnancy because they can reduce risk of preeclampsia and other negative health outcomes.
Persistent COVID-19 Symptoms Objectively Linked to Worse Cognition
Individuals with persistent COVID-19 symptoms had an objectively greater cognitive deficit than individuals had never had COVID-19.
