CLINICAL ROLE -
Melanoma Drug Benefits Some Lung Cancer Patients
BRAF mutations commonly found in melanoma also seen in subset of lung cancer patients.
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Experimental Hepatitis C Drug Shows 95% Cure Rates in Previously Untreated Patients
Merck's once-daily treatment regimen of grazoprevir and elbasvir may bring added competition to HCV drug market.
Breakthrough Causes Cancer Cells to Turn Back into Normal Cells
Introduction of protein to pancreatic cancer cells causes them to revert back to normal.
Missing Genetic Link Discovery May Lead to New Treatments for RA, Diabetes
Gene may help identify clue to separation of overactive and underactive immune activity.
High Cost Rheumatoid Arthritis Drugs Create Large Burden for Patients
Nearly 30% of total biologic drug costs paid out-of-pocket.
Link Found Between Cancer and Dietary Supplement Use
Taking over-the-counter supplements beyond the recommended amount could increase cancer risk.
Drug Combination Overcomes Breast Cancer Treatment Resistance
Suppression of Wnt signaling pathway shows promise.
Relapse Occurs When Multiple Sclerosis Patients Stop Taking Medication
Long term implications result when patients stop taking disease-modifying drugs.
Cancer Drug May Cure Hepatitis B
An antiviral and anti-cancer drug combination was 100% effective in preclinical trials.
Robust Drug Pipeline Highlights Specialty Pharmacy Week in Review
Top stories of the week on Specialty Pharmacy Times from April 20 to April 24.
Gene Therapy for Rare Immune System Disease Shows Promise
Wiskott-Aldrich treatment shows robust clinical effect.
Altered Lupus Antibodies May Become Cancer Killers
Re-engineering antibodies allows them to selectively kill tumors.
Adherence is Paramount in Era of Rising Specialty Drug Costs
Catamaran chief medical officer discusses various trends that will impact specialty medications into the future.
MS Drug Combination Repairs Damaged Brain Cells, Reverses Paralysis
Topical medications that treat skin conditions prompt stem cells in the brain to repair damage.
Protein Inhibition Therapy Holds Promise for Treating Several Cancer Types
Regulating PD-L1 protein that helps cancer evade immune system suggests new therapeutic approach.
HIV-Infected Men More Sensitive to Alcohol
Patients should be counseled that there is no safe level of alcohol consumption.
Immune System Regulation May Help Control Rheumatoid Arthritis, Diabetes
Novel pathway regulating immune cell movement may help eliminate debilitating effects of several serious diseases.
Extending Dose of Multiple Sclerosis Drug Safe and Effective
Pushing treatment with natalizumab from 4 weeks up to 8 weeks shows promising results.
Why Do African Americans Have Worse Breast Cancer Outcomes?
Researchers determine mechanism for poor survival rates in African American patients with estrogen-receptor positive breast cancer.
Walking Can Help Reduce Prostate Cancer Treatment Side Effects
Mild exercise found to improve fatigue and depression.
Multiple Sclerosis Drug Effective Fighting HIV Viral Reservoir
Medication also used in treatment of Crohn's disease effective at blocking pathways.
PTSD Contributes to Chemobrain in Cancer Patients
Mild cognitive impairment can set in prior to the start of therapy.
Specialty Drugs Dominate Late-Stage Pipeline
Record number of orphan drugs approved in 2014.
Epilepsy Drug Protects Eyesight of Multiple Sclerosis Patients
Phenytoin helps to reduce damage to the nerve fiber.
Repurposed Anti-Fungal Drug Offers Potential New Prostate Cancer Treatment
Itraconazole shows some promise in treatment of metastatic prostate cancer.
Orphan drugs and breakthrough therapies last year comprised the highest number of new medications approved since 2001.
Racial Disparities in Cancer Death Rate Declining
Mortality gap in cancer deaths among African Americans and Caucasians may eventually disappear.
Otezla Shows Promise in Treatment of Rare Inflammatory Disease
Treatment found to improve several measures of disease activity and quality of life in patients with Behçet's disease.
Synthetic Marijuana May Cause Cancer
Study suggests substances in synthetic marijuana may damage human cell DNA.
Experimental Multiple Sclerosis Drug May Repair Nerve Damage
Researchers find biological evidence of repaired myelin.