CLINICAL ROLE -
Ashley Gallagher is an assistant editor at Pharmacy Times®. She graduated from St. Bonaventure University in 2020 in journalism and mass communications. Previously, she worked as a pharmacy technician for a retail chain.
First Generation COVID-19 Vaccine Protection Wanes Over Time
Investigators estimate that the effectiveness was higher after 1 or 2 booster doses compared with the primary series alone.
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GSK Announces Positive Pivotal Phase 3 Data for 5-in-1 Meningococcal Vaccine Candidate
MenABCWY combination meets all 11 primary endpoints and shows that it is well tolerated, with a safety profile consistent with MenACWY (Menveo) and MenB (Bexsero).
Janssen’s Xarelto Demonstrates Consistent Benefits for PAD for Up to 3 Years
Rivaroxaban and aspirin results in a 33% reduction in major adverse limb events both early and late following lower extremity revascularization.
Enhertu Demonstrates Positive Results Across Multiple HER2-Expressing Tumor Types
Trastuzumab deruxtecan from AstraZeneca and Daiichi Sankyo meets prespecified criteria for duration of response and objective response rate.
Novo Nordisk Lowers Insulin Price for Up to 75% for Individuals With Diabetes
The changes, which will be effective January 1, 2024, include pre-filled pens, vials of basal, vials of bolus, and pre-mix insulins.
Nasal Foralumab Shows Promise in Regulating Inflammatory Response of COVID-19
Study includes healthy individuals and those who had progressive multiple sclerosis with the nasally administered treatment.
Rural-Urban Access to Telemedicine Remains Divided for Veteran Affairs Care
The COVID-19 pandemic was associated with an increase in rural-urban telemedicine divide across the Veteran Affairs health care system.
Solanezumab Does Not Slow Progression of Cognitive Decline in Preclinical Alzheimer Disease
Eli Lilly treatment targets soluble amyloid beta and did not clear plaque or halt accumulation of amyloid in individuals treated with the drug in the A4 study.
Study: Long-Term Effects of Acute Pneumococcal Infection Reduce Quality of Life
These infections can include the central nervous system (CNS), circulation, invaded organs, lower airway, and the middle ear, with outcomes that can be permanent.
FDA Accepts sNDA for Empagliflozin to Lower Blood Sugar in Young Children With T2D
The application is based on phase 3 results from the DINAMO trial showing that Jardiance tablets significantly reduced A1C levels vs a placebo in participants aged 10 to 17 years.
FDA Accepts sBLA for Dupilumab as Treatment for Those With Chronic Spontaneous Urticaria
More than 300,000 individuals in the United States have CSU that is inadequately controlled by antihistamines.
Review Suggests Several Promising Prophylaxis Treatments for Clostridioides difficile Infection
Including probiotics and antibiotics, such as fidaxomicin and vancomycin, could help prevent CDI, but more research is needed to evaluate them, investigators say.
Experimental Treatment for Severe Myotoxicity Shows Promise for Individuals With Cancer
Therapy consists of high-dose abatacept, ruxolitinib, and proactive monitoring for respiratory muscle involvement.
Long-Acting ART Suppresses HIV in Individuals Without Virological Suppression
Study results indicates that the injectable antiretroviral therapy can benefit patients who are historically underserved and may face treatment barriers, including those with mental illness.
Pfizer, BioNTech Submit sBLA for Omicron BA.4/BA.5-Adapted Bivalent COVID-19 Vaccine
Companies seek FDA approval for individuals aged 12 years and older to receive vaccinations for their primary series.
Zavegepant Meets Co-Primary Endpoints for Treatment of Acute Migraines in Adults
Zavegepant is the first calcitonin gene-related peptide receptor for migraines in development as an intranasal formulation studied in a phase 3 trial.
GSK’s Respiratory Syncytial Virus Vaccine Candidate Meets Primary Efficacy Endpoint
Phase 3 trial results indicate efficacy against respiratory syncytial virus-lower respiratory tract disease in individuals aged 60 years and older.
Nivolumab Plus Cabozantinib Demonstrates Positive Results for Renal Cell Carcinoma
Data show continued objective response rate, overall survival, and progression-free survival benefits of nivolumab plus cabozantinib in the treatment of advanced renal cell carcinoma.
Weight Problems Affect Americans With T1D Almost as Often as General Population
Findings highlight the need for evidence-based strategies to avoid being obese or overweight for patients with type 1 diabetes, which is often considered a disease of thin individuals.
Study: Individuals Who Knew Someone With COVID-19 Are More Likely to Get Vaccinated
Approximately 48.1% of those who received vaccines had family members or friends who were either sick or recovered from the illness compared with 26.9% who were unvaccinated.
Faulty Genes May Cause Multisystem Inflammatory Syndrome in Children
The findings are the first to explain the mechanisms of any Kawasaki disease, a rare childhood inflammatory condition that is triggered by different viruses.
Early Stages of Injectable PrEP Implant Show Promise in Complete Protection Against HIV
The latest data indicate that the formulation can provide up to 6 months of full protection against multiple virus challenges.
NCPA Video Series Helps Pharmacists Expand Their Practices
First season of makeover show follows 5 pharmacies building immunization programs.
Celebrating Black History Month: Organization Supports Black Health System Pharmacists
Association of Black Health-System Pharmacists focuses on advocacy, collaboration, education, leadership, and research.
Cochrane Review: Vitamin D Supplements Do Not Reduce Risk of Asthma Attacks
The new findings, which include updated data, contradict results of a previous analysis by the same investigators.
Patients With Hidradenitis Suppurativa Treated With Novartis’ Cosentyx Show Improvement
Results of 2 phase 3 clinical trials demonstrate better response rate beyond the primary endpoint analysis at week 16 to more than 55 at week 55.
Study: State Policies Legalizing Cannabis Show No Links to Psychosis-Related Outcomes
Investigators focus on whether legalization of the drug is associated with an increase in health care use for the psychotic disorder.
Worse Brain MRI, Neurodevelopmental Outcomes Show No Link to dDNV Genes
The association with subgroups of gene variations based on expression or function should be assessed in larger studies, investigators say.
Healthy Lifestyles May Lower Risk of Microvascular Complications
Study results indicate that exercising, following a high-quality diet, limiting alcohol intake, maintaining a healthy body weight, and not smoking protects those with type 2 diabetes.
Study: Gum Disease Shows Link to Atrial Fibrosis
Worse cases of periodontitis demonstrate association with progression of the scarring of the heart’s left atrium, data indicate.