A new report adds evidence that vitamin E acetate may play a role in the vaping-related illnesses and vaping-associated lung injury (EVALI) that have affected some e-cigarette users, STAT reported. According to the article, Minnesota health officials tested 10 THC-containing vaping products seized by law enforcement in 2018, before the EVALI outbreak began, and 20 seized from a raid in 2019. The analysis found that none of the product from 2018 tested positive for vitamin E acetate, but all of the products in 2019 did, the article reported. The report’s authors noted that there’s a need for more research to determine whether inhaled vitamin E acetate is directly causing cases of EVALI.
Long-term data demonstrated better outcomes for certain patients with lung cancer treated with brigatinib (Alunbrig, Takeda) compared with crizotinib (Xalkori, Pfizer), Reuters reported. According to the article, the results, which were released at the European Society for Medical Oncology Asia Congress in Singapore, were a 25-month follow up to a phase 3 trial which focused on patients with advanced anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer who had not received a prior ALK inhibitor. Overall, the data showed that brigatinib reduced the risk of disease progression by 76% in patients whose cancer had spread to the brain and by 57% in all patients compared with crizotinib, the article reported.