Opinion|Videos|August 13, 2026
Translating TONES Trial Data Into Meaningful Patient Outcome
Fact checked by: Ron Panarotti
Winter breaks down the TONES clinical trial program, discussing ESS and Maintenance of Wakefulness Test end points. He covers how these benchmarks translate into what patients actually experience as functional improvements in their daily lives—helping pharmacists understand the real-world significance of the trial data.
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W. Christopher Winter, MD, neurologist and sleep specialist at Charlottesville Neurology and Sleep Medicine, breaks down the TONES clinical trial program, discussing ESS and Maintenance of Wakefulness Test end points. He covers how these benchmarks translate into what patients actually experience as functional improvements in their daily lives—helping pharmacists understand the real-world significance of the trial data.
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