
Opinion|Videos|August 13, 2026
TONES 5 and Long-Term Durability: Does Efficacy Sustain Over Time?
Winter examines the TONES 5 randomized-withdrawal trial, discussing how sustained efficacy over 6 months factors into clinical decision-making and patient adherence in a chronic condition like EDS.
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Winter examines the TONES 5 randomized-withdrawal trial, discussing how sustained efficacy over 6 months factors into clinical decision-making and patient adherence in a chronic condition like EDS. He emphasizes durability as a key consideration for long-term therapy success.
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