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|Articles|December 9, 2021
Pharmacy Clinical Pearl of the Day: Factor V Leiden
Author(s)Saro Arakelians, PharmD
Factor V Leiden can increase the chance of developing abnormal blood clots, most commonly in the legs or lungs.
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Clinical Pearl of the Day: Factor V Leiden
Factor V Leiden is a mutation of one of the clotting factors in the blood.
Insight:
- This mutation can increase the chance of developing abnormal blood clots, most commonly in the legs or lungs.
- Most people with factor V Leiden never develop abnormal clots. But in those who do, these abnormal clots can lead to long-term health problems or become life-threatening.
- Both men and women can have factor V Leiden. Women who carry the factor V Leiden mutation may have an increased tendency to develop blood clots during pregnancy or when taking the hormone estrogen.
- Symptoms may include pain, swelling, redness, and warmth.
- Risk factors may include having 2 faulty genes, immobility, taking estrogens, and in patients with blood types A, B, or AB.
- Treatment may include a short course of blood thinners, leg wraps that inflate and deflate to keep blood moving in your legs, compression stockings, and going for walks soon after surgery.
- These patients should avoid sports with too much contact, use a soft toothbrush, and be cautious with household tasks.
Sources:
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