News|Videos|June 5, 2026

Oncology PulsePoints: Metastatic CRPC ASCO Living Guidelines Updates

Fact checked by: Kirsty Mackay

Vince Sung, PharmD, MBA, BCOP, BCPS, discusses the clinical implications of the updated prostate cancer guidelines.

The 2024 American Society of Clinical Oncology (ASCO) living guideline update for metastatic castration-resistant prostate cancer (mCRPC) represents more than just the addition of new therapies—it marks a definitive shift toward biomarker-driven treatment sequencing. Vince Sung, PharmD, MBA, BCOP, BCPS, director of pharmacy in oncology and infusion at Ascension St. John in Tulsa, breaks down the 3 practice-changing phase 3 trials incorporated into the update, what they mean for clinical workflow, and why pharmacists are uniquely positioned to bridge the gap between guideline recommendations and real-world implementation.