From Resistance to Response: The Microbiome’s Role in Optimizing Cancer Therapy

Author(s)Alexandra Gerlach, Senior Content Producer

Explore how the gut microbiome influences cancer therapy responses, resistance mechanisms, and the potential of microbiota-focused strategies for improved outcomes.

Resistance remains one of the most significant barriers to optimal treatment outcomes and overall survival for patients across cancer types. Although genetic mutations play a key role in poor therapeutic responses, the gut microbiome may also interfere with critical therapies in the cancer treatment landscape. Studies show that disruptions in gut microbiota are associated with resistance and less favorable responses to immunotherapies.